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This gene encodes a member of the inorganic phosphate transporter family. The encoded protein is a type 3 sodium-dependent phosphate symporter that plays an important role in phosphate homeostasis by mediating cellular phosphate uptake. The encoded protein also confers susceptibility to viral infection as a gamma-retroviral receptor. Mutations in this gene may play a role in familial idiopathic basal ganglia calcification. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
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Protein Aliases: Gibbon ape leukemia virus receptor 2; GLVR-2; hPit2; murine leukemia virus, amphotropic, receptor for; murine leukemia virus, amphotropic; receptor; Phosphate transporter 2; PiT-2; Sodium-dependent phosphate transporter 2; solute carrier family 20 (phosphate transporter), member 2; Solute carrier family 20 member 2; Type III sodium-dependent phosphate transporter
Gene Aliases: GLVR-2; GLVR2; IBGC1; IBGC3; MLVAR; MolPit2; PIT-2; PIT2; Ram-1; RAM1; SLC20A2