Immunogen sequence: LPETMSSSPT AASTTHRYPK TPSPTVAHES NWAKCEDLET QTQSEKQLVL NLTGNTLCAG GASDEKLISL ICRAVKATFN PAQDKCGIRL ASVPGSQTVV VKEITIHTKL PAKDVYERLK DKWDELKEAG VSDMKLGD
Podolyxin is a CD34 family member expressed by podocytes, vascular endothelium, mesothelium, and a subset of hematopoietic progenitors. It is the major sialoprotein in the glycocalyx of glomerular podocytes. The physiologic role of podolyxin in leukemic blasts is unknown. However, it is thought of as a candidate prostate cancer tumor aggressiveness gene. Podolyxin appears to complement CD34 as a useful cell surface marker for hemangioblasts, the common precursors of hematopoietic and endothelial cells.
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Protein Aliases: GCTM-2 antigen; Gp200; PC; PCLP; PCLP-1; Podocalyxin; podocalyxin-like; Podocalyxin-like protein 1
Gene Aliases: Gp200; PC; PCLP; PCLP-1; PCLP1; PODXL
UniProt ID: (Human) O00592
Entrez Gene ID: (Human) 5420