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Proteintech
POLR3B Polyclonal Antibody
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Product Details
16574-1-AP
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
POLR3B Fusion Protein Ag9856 (794-1133 aa encoded by BC046238)
Conjugate
Form
Liquid
Concentration
0.13 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MLDAATRKP IWRHEILDAD GICSPGEKVE NKQVLVNKSM PTVTQIPLEG SNVPQQPQYK DVPITYKGAT DSYIEKVMIS SNAEDAFLIK MLLRQTRRPE IGDKFSSRHG QKGVCGLIVP QEDMPFCDSG ICPDIIMNPH GFPSRMTVGK LIELLAGKAG VLDGRFHYGT AFGGSKVKDV CEDLVRHGYN YLGKDYVTSG ITGEPLEAYI YFGPVYYQKL KHMVLDKMHA RARGPRAVLT RQPTEGRSRD GGLRLGEMER DCLIGYGASM LLLERLMISS DAFEVDVCGQ CGLLGYSGWC HYCKSSCHVS SLRIPYACKL LFQELQSMNI IPRLKLSKYN E (794-1133 aa encoded by BC046238)
Target Information
POLR3B (RNA Polymerase III Subunit B) is a Protein Coding gene. Diseases associated with POLR3B include Leukodystrophy, Hypomyelinating, 8, With Or Without Oligodontia And/Or Hypogonadotropic Hypogonadism and Cerebellar Hypoplasia With Endosteal Sclerosis. Among its related pathways are RNA Polymerase II Transcription Initiation And Promoter Clearance and ATP/ITP metabolism. Gene Ontology (GO) annotations related to this gene include DNA-directed 5'-3' RNA polymerase activity and ribonucleoside binding. An important paralog of this gene is POLR2B.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: C128; DNA-directed RNA polymerase III 127.6 kDa polypeptide; DNA-directed RNA polymerase III B; DNA-directed RNA polymerase III subunit B; DNA-directed RNA polymerase III subunit RPC2; FLJ10388; interphase nucleus and mitotic apparatus associated protein; polymerase (RNA) III (DNA directed) polypeptide B; polymerase (RNA) III subunit B; RNA polymerase III subunit C2; RNA polymerase III subunit RPC2 homolog
Gene Aliases: 2700078H01Rik; A330032P03Rik; C128; C85372; HLD8; INMAP; POLR3B; RGD1565311; RPC2
UniProt ID: (Human) Q9NW08, (Mouse) P59470
Entrez Gene ID: (Human) 55703, (Mouse) 70428, (Rat) 362858
transcription from RNA polymerase III promoter
positive regulation of type I interferon production
positive regulation of interferon-beta production
innate immune response
positive regulation of innate immune response
defense response to virus
immune system process
transcription, DNA-templated
biological_process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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