Invitrogen

PR3 Polyclonal Antibody

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PR3 Antibody in Immunohistochemistry (IHC) — Immunohistochemical analysis of PR3 in human bone marrow and cerebral cortex tissues using a PR3 polyclonal antibody (Product # PA5-82223). Corresponding RNA-seq data are presented for the same tissues.

PR3 Antibody in Western Blot (WB) — Western blot analysis of PR3 by a PR3 polyclonal antibody (Product # PA5-82223). Analysis in control (vector only transfected HEK293T lysate) and PRTN3 over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (~3.1 kDa) in mammalian HEK293T cells, LY400985).

Product Details

Tested Applications

Dilution

Immunohistochemistry (Paraffin) (IHC (P))

1:200-1:500

Western Blot (WB)

0.4 µg/mL

Product Specifications

Species Reactivity

Human

Host / Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human PRTN3

Conjugate

Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Product Specific Information

Immunogen sequence: PTQQHFSVAQ VFLNNYDAEN KLNDILLIQL SSPANLSASV ATVQLPQQDQ PVPHGTQCLA MGWGRVGAHD PPAQVLQELN VTVVTFFCRP HNICTFVPRR KAGICFGDSG GPLICDGI

Target Information

Proteinase 3 plays a role in neutrophil response to inflammation.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Bioinformatics

Protein Aliases: ACPA; AGP7; azurophil granule protein 7; C-ANCA; C-ANCA antigen; Leukocyte proteinase 3; MBT; Myeloblastin; Neutrophil proteinase 4; NP-4; P29; PR-3; serine proteinase, neutrophil; Wegener autoantigen; Wegener granulomatosis autoantigen

Gene Aliases: ACPA; AGP7; C-ANCA; CANCA; MBN; MBT; NP-4; NP4; P29; PR-3; PR3; PRTN3

UniProt ID: (Human) P24158

Entrez Gene ID: (Human) 5657

Molecular Function: hydrolase protease serine protease