Recommended positive controls: 293T, A431, Jurkat, Raji.
Predicted reactivity: Mouse (91%), Bovine (92%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Guanine nucleotide exchange factor (GEF) with specificity for RAP2A, KRAS, HRAS, and NRAS (in vitro). Plays a role in cell migration.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CG4853 gene product; Ras-GEF domain-containing family member 1A; RasGEF domain family, member 1A
Gene Aliases: CG4853; RASGEF1A
UniProt ID: (Human) Q8N9B8
Entrez Gene ID: (Human) 221002
Molecular Function: guanyl-nucleotide exchange factor