Proteintech

RHOC Polyclonal Antibody

Product Image Gallery

RHOC Antibody in Western Blot (WB) — NIH/3T3 cells were subjected to SDS PAGE followed by western blot with 10632-1-AP (RHOC antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours.

Product Details

10632-1-AP

Applications	Tested Dilution	Publications
Western Blot (WB)	1:500-1:1,000	View 8 publications 8 publications
Immunohistochemistry (IHC)	Assay-dependent	View 1 publication 1 publication
Miscellaneous PubMed (Misc)	-	View 1 publication 1 publication

Product Specifications
Species Reactivity	Human, Mouse, Rat
Published species	Human
Host/Isotype	Rabbit / IgG
Class	Polyclonal
Type	Antibody
Immunogen	RHOC Fusion Protein Ag0988 (1-193 aa encoded by BC007245) View antigen
Conjugate	Unconjugated
Form	Liquid
Concentration	0.2 mg/mL
Purification	Antigen affinity chromatography
Storage buffer	PBS, pH 7.3, with 50% glycerol
Contains	0.1% sodium azide
Storage conditions	-20°C

Product Specific Information

Immunogen sequence: MAAIRKKLV IVGDGACGKT CLLIVFSKDQ FPEVYVPTVF ENYIADIEVD GKQVELALWD TAGQEDYDRL RPLSYPDTDV ILMCFSIDSP DSLENIPEKW TPEVKHFCPN VPIILVGNKK DLRQDEHTRR ELAKMKQEPV RSEEGRDMAN RISAFGYLEC SAKTKEGVRE VFEMATRAGL QVRKNKRRRG CPIL (1-193 aa encoded by BC007245)

Target Information

RhoC is part of blood-group antigens that are generally defined as molecules formed by sequential addition of saccharides to the carbohydrate side chains of lipids and proteins detected on erythrocytes and certain epithelial cells. The A, B and H antigens are reported to undergo modulation during malignant cellular transformation. Blood group related antigens represent a group of carbohydrate determinants carried on both glycolipids and glycoproteins. They are usually mucin-type, and are detected on erythrocytes, certain epithelial cells, and in secretions of certain individuals. Sixteen genetically and biosynthetically distinct but inter-related specificities belong to this group of antigens, including A, B, H, Lewis A, Lewis B, Lewis X, Lewis Y, and precursor type 1 chain antigens.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

High Expression of lncRNA AFAP1-AS1 Promotes the Progression of Colon Cancer and Predicts Poor Prognosis.

Journal of Cancer

Bo H,Fan L,Li J,Liu Z,Zhang S,Shi L,Guo C,Li X,Liao Q,Zhang W,Zhou M,Xiang B,Li X,Li G,Xiong W,Zeng Z,Xiong F,Gong Z

Thu Oct 01 00:00:00 EDT 2020

Long non-coding RNA MT1DP shunts the cellular defense to cytotoxicity through crosstalk with MT1H and RhoC in cadmium stress.

Cell discovery

Gao M,Chen M,Li C,Xu M,Liu Y,Cong M,Sang N,Liu S

Thu Oct 01 00:00:00 EDT 2020

Long noncoding RNA AFAP1-AS1 acts as a competing endogenous RNA of miR-423-5p to facilitate nasopharyngeal carcinoma metastasis through regulating the Rho/Rac pathway.

Journal of experimental & clinical cancer research : CR

Lian Y,Xiong F,Yang L,Bo H,Gong Z,Wang Y,Wei F,Tang Y,Li X,Liao Q,Wang H,Zhou M,Xiang B,Wu X,Li Y,Li X,Chen X,Li G,Guo C,Zeng Z,Xiong W

Tue Oct 16 00:00:00 EDT 2018

The role of the long non-coding RNA TDRG1 in epithelial ovarian carcinoma tumorigenesis and progression through miR-93/RhoC pathway.

Molecular carcinogenesis

Chen S,Wang LL,Sun KX,Xiu YL,Zong ZH,Chen X,Zhao Y

Thu Feb 01 00:00:00 EST 2018

The role of the long non-coding RNA TDRG1 in epithelial ovarian carcinoma tumorigenesis and progression through miR-93/RhoC pathway.

Molecular carcinogenesis

Chen S,Wang LL,Sun KX,Xiu YL,Zong ZH,Chen X,Zhao Y

Thu Feb 01 00:00:00 EST 2018

The role of long non-coding RNA PCA3 in epithelial ovarian carcinoma tumorigenesis and progression.

Gene

Liu Y,Zong ZH,Guan X,Wang LL,Zhao Y

Mon Oct 30 00:00:00 EDT 2017

Effects and mechanism of RhoC downregulation in suppressing ovarian cancer stem cell proliferation, drug resistance, invasion and metastasis.

Oncology reports

Sang XB,Sun KX,Wang LL,Chen S,Wu DD,Zong ZH,Zhao Y

Thu Dec 01 00:00:00 EST 2016

AFAP1-AS1, a long noncoding RNA upregulated in lung cancer and promotes invasion and metastasis.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine

Zeng Z,Bo H,Gong Z,Lian Y,Li X,Li X,Zhang W,Deng H,Zhou M,Peng S,Li G,Xiong W

Fri Jan 01 00:00:00 EST 2016

Upregulated long non-coding RNA AFAP1-AS1 expression is associated with progression and poor prognosis of nasopharyngeal carcinoma.

Oncotarget

Bo H,Gong Z,Zhang W,Li X,Zeng Y,Liao Q,Chen P,Shi L,Lian Y,Jing Y,Tang K,Li Z,Zhou Y,Zhou M,Xiang B,Li X,Yang J,Xiong W,Li G,Zeng Z

Fri Aug 21 00:00:00 EDT 2015

Overexpression of RNF146 in non-small cell lung cancer enhances proliferation and invasion of tumors through the Wnt/β-catenin signaling pathway.

PloS one

Gao Y,Song C,Hui L,Li CY,Wang J,Tian Y,Han X,Chen Y,Tian DL,Qiu X,Wang E

Wed Sep 17 00:00:00 EDT 2014

Bioinformatics

Protein Aliases: aplysia ras-related homolog 9 (RhoC); AR ARHC; h9; MGC1448; MGC61427; oncogene RHO H9; ras homolog 9 (RhoC); ras homolog gene family, member C; RAS-related homolog 9; Rho; Rho cDNA clone 9; RHO MGC1448; Rho-related GTP-binding protein RhoC; rhoC GTPase; SIG-61; Silica-induced gene 61 protein; small GTP binding protein RhoC

Gene Aliases: AI324259; ARH9; ARHC; H9; RHOC; RHOH9

UniProt ID: (Human) P08134, (Mouse) Q62159

Entrez Gene ID: (Human) 389, (Mouse) 11853, (Rat) 295342

Molecular Function: small GTPase