Proteintech

RHOC Polyclonal Antibody

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RHOC Antibody (10632-1-AP) in WB

Various lysates were subjected to SDS PAGE followed by western blot with (Product # 10632-1-AP) (RHOC antibody) at dilution of 1:8000 incubated at room temperature for 1.5 hours.

Product Image Gallery

Product Details

10632-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

View 15 publications 15 publications

Immunohistochemistry (IHC)

Assay-dependent

View 2 publications 2 publications

Miscellaneous PubMed (Misc)

View 1 publication 1 publication

Not applicable (N/A)

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

RHOC Fusion Protein Ag0988 (1-193 aa encoded by BC007245)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.2 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: MAAIRKKLV IVGDGACGKT CLLIVFSKDQ FPEVYVPTVF ENYIADIEVD GKQVELALWD TAGQEDYDRL RPLSYPDTDV ILMCFSIDSP DSLENIPEKW TPEVKHFCPN VPIILVGNKK DLRQDEHTRR ELAKMKQEPV RSEEGRDMAN RISAFGYLEC SAKTKEGVRE VFEMATRAGL QVRKNKRRRG CPIL (1-193 aa encoded by BC007245)

Target Information

RhoC is part of blood-group antigens that are generally defined as molecules formed by sequential addition of saccharides to the carbohydrate side chains of lipids and proteins detected on erythrocytes and certain epithelial cells. The A, B and H antigens are reported to undergo modulation during malignant cellular transformation. Blood group related antigens represent a group of carbohydrate determinants carried on both glycolipids and glycoproteins. They are usually mucin-type, and are detected on erythrocytes, certain epithelial cells, and in secretions of certain individuals. Sixteen genetically and biosynthetically distinct but inter-related specificities belong to this group of antigens, including A, B, H, Lewis A, Lewis B, Lewis X, Lewis Y, and precursor type 1 chain antigens.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

GTPBP2 positively regulates the invasion, migration and proliferation of non-small cell lung cancer.

Journal of Cancer

Jie L,Cong L,Conghui W,Ying G

Tue Jun 08 00:00:00 UTC 2021

Hsa_circ_001659 serves as a novel diagnostic and prognostic biomarker for colorectal cancer.

Biochemical and biophysical research communications

He B,Chao W,Huang Z,Zeng J,Yang J,Luo D,Huang S,Pan H,Hao Y

Fri Apr 30 00:00:00 UTC 2021

The association of transcription factor Prox1 with the proliferation, migration, and invasion of lung cancer.

Open life sciences

Hao X,Luo W,Qiu X

Sun Apr 24 00:00:00 UTC 2022

CUX1 Facilitates the Development of Oncogenic Properties Via Activating Wnt/β-Catenin Signaling Pathway in Glioma.

Frontiers in molecular biosciences

Feng F,Zhao Z,Zhou Y,Cheng Y,Wu X,Heng X

Tue Aug 24 00:00:00 UTC 2021

Cytotoxic necrotizing factor 1 promotes bladder cancer angiogenesis through activating RhoC.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Guo Y,Wang J,Zhou K,Lv J,Wang L,Gao S,Keller ET,Zhang ZS,Wang Q,Yao Z

Mon Jun 01 00:00:00 UTC 2020

RALY may cause an aggressive biological behavior and a dismal prognosis in non-small-cell lung cancer.

Experimental cell research

Song G,Guo G,Du T,Li X,Wang J,Yan Y,Zhao Y

Wed Apr 15 00:00:00 UTC 2020

TMED3 Promotes Proliferation and Migration in Breast Cancer Cells by Activating Wnt/β-Catenin Signaling.

OncoTargets and therapy

Zhang X,Luo Y,Li Q

Fri Apr 15 00:00:00 UTC 2022

Autophagy regulates exosome secretion in rat nucleus pulposus cells via the RhoC/ROCK2 pathway.

Experimental cell research

Hu SQ,Zhang QC,Meng QB,Hu AN,Zou JP,Li XL

Thu Oct 15 00:00:00 UTC 2020

The role of the long non-coding RNA TDRG1 in epithelial ovarian carcinoma tumorigenesis and progression through miR-93/RhoC pathway.

Molecular carcinogenesis

Chen S,Wang LL,Sun KX,Xiu YL,Zong ZH,Chen X,Zhao Y

Thu Feb 01 00:00:00 UTC 2018

The role of the long non-coding RNA TDRG1 in epithelial ovarian carcinoma tumorigenesis and progression through miR-93/RhoC pathway.

Molecular carcinogenesis

Chen S,Wang LL,Sun KX,Xiu YL,Zong ZH,Chen X,Zhao Y

Thu Feb 01 00:00:00 UTC 2018

The role of the long non-coding RNA TDRG1 in epithelial ovarian carcinoma tumorigenesis and progression through miR-93/RhoC pathway.

Molecular carcinogenesis

Chen S,Wang LL,Sun KX,Xiu YL,Zong ZH,Chen X,Zhao Y

Thu Feb 01 00:00:00 UTC 2018

The role of the long non-coding RNA TDRG1 in epithelial ovarian carcinoma tumorigenesis and progression through miR-93/RhoC pathway.

Molecular carcinogenesis

Chen S,Wang LL,Sun KX,Xiu YL,Zong ZH,Chen X,Zhao Y

Thu Feb 01 00:00:00 UTC 2018

High Expression of lncRNA AFAP1-AS1 Promotes the Progression of Colon Cancer and Predicts Poor Prognosis.

Journal of Cancer

Bo H,Fan L,Li J,Liu Z,Zhang S,Shi L,Guo C,Li X,Liao Q,Zhang W,Zhou M,Xiang B,Li X,Li G,Xiong W,Zeng Z,Xiong F,Gong Z

Thu Oct 01 00:00:00 UTC 2020

High Expression of lncRNA AFAP1-AS1 Promotes the Progression of Colon Cancer and Predicts Poor Prognosis.

Journal of Cancer

Bo H,Fan L,Li J,Liu Z,Zhang S,Shi L,Guo C,Li X,Liao Q,Zhang W,Zhou M,Xiang B,Li X,Li G,Xiong W,Zeng Z,Xiong F,Gong Z

Thu Oct 01 00:00:00 UTC 2020

Long non-coding RNA MT1DP shunts the cellular defense to cytotoxicity through crosstalk with MT1H and RhoC in cadmium stress.

Cell discovery

Gao M,Chen M,Li C,Xu M,Liu Y,Cong M,Sang N,Liu S

Thu Oct 01 00:00:00 UTC 2020

Long non-coding RNA MT1DP shunts the cellular defense to cytotoxicity through crosstalk with MT1H and RhoC in cadmium stress.

Cell discovery

Gao M,Chen M,Li C,Xu M,Liu Y,Cong M,Sang N,Liu S

Thu Oct 01 00:00:00 UTC 2020

Long noncoding RNA AFAP1-AS1 acts as a competing endogenous RNA of miR-423-5p to facilitate nasopharyngeal carcinoma metastasis through regulating the Rho/Rac pathway.

Journal of experimental & clinical cancer research : CR

Lian Y,Xiong F,Yang L,Bo H,Gong Z,Wang Y,Wei F,Tang Y,Li X,Liao Q,Wang H,Zhou M,Xiang B,Wu X,Li Y,Li X,Chen X,Li G,Guo C,Zeng Z,Xiong W

Tue Oct 16 00:00:00 UTC 2018

Long noncoding RNA AFAP1-AS1 acts as a competing endogenous RNA of miR-423-5p to facilitate nasopharyngeal carcinoma metastasis through regulating the Rho/Rac pathway.

Journal of experimental & clinical cancer research : CR

Lian Y,Xiong F,Yang L,Bo H,Gong Z,Wang Y,Wei F,Tang Y,Li X,Liao Q,Wang H,Zhou M,Xiang B,Wu X,Li Y,Li X,Chen X,Li G,Guo C,Zeng Z,Xiong W

Tue Oct 16 00:00:00 UTC 2018

The role of long non-coding RNA PCA3 in epithelial ovarian carcinoma tumorigenesis and progression.

Gene

Liu Y,Zong ZH,Guan X,Wang LL,Zhao Y

Mon Oct 30 00:00:00 UTC 2017

The role of long non-coding RNA PCA3 in epithelial ovarian carcinoma tumorigenesis and progression.

Gene

Liu Y,Zong ZH,Guan X,Wang LL,Zhao Y

Mon Oct 30 00:00:00 UTC 2017

Effects and mechanism of RhoC downregulation in suppressing ovarian cancer stem cell proliferation, drug resistance, invasion and metastasis.

Oncology reports

Sang XB,Sun KX,Wang LL,Chen S,Wu DD,Zong ZH,Zhao Y

Thu Dec 01 00:00:00 UTC 2016

Effects and mechanism of RhoC downregulation in suppressing ovarian cancer stem cell proliferation, drug resistance, invasion and metastasis.

Oncology reports

Sang XB,Sun KX,Wang LL,Chen S,Wu DD,Zong ZH,Zhao Y

Thu Dec 01 00:00:00 UTC 2016

AFAP1-AS1, a long noncoding RNA upregulated in lung cancer and promotes invasion and metastasis.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine

Zeng Z,Bo H,Gong Z,Lian Y,Li X,Li X,Zhang W,Deng H,Zhou M,Peng S,Li G,Xiong W

Fri Jan 01 00:00:00 UTC 2016

AFAP1-AS1, a long noncoding RNA upregulated in lung cancer and promotes invasion and metastasis.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine

Zeng Z,Bo H,Gong Z,Lian Y,Li X,Li X,Zhang W,Deng H,Zhou M,Peng S,Li G,Xiong W

Fri Jan 01 00:00:00 UTC 2016

Upregulated long non-coding RNA AFAP1-AS1 expression is associated with progression and poor prognosis of nasopharyngeal carcinoma.

Oncotarget

Bo H,Gong Z,Zhang W,Li X,Zeng Y,Liao Q,Chen P,Shi L,Lian Y,Jing Y,Tang K,Li Z,Zhou Y,Zhou M,Xiang B,Li X,Yang J,Xiong W,Li G,Zeng Z

Fri Aug 21 00:00:00 UTC 2015

Upregulated long non-coding RNA AFAP1-AS1 expression is associated with progression and poor prognosis of nasopharyngeal carcinoma.

Oncotarget

Bo H,Gong Z,Zhang W,Li X,Zeng Y,Liao Q,Chen P,Shi L,Lian Y,Jing Y,Tang K,Li Z,Zhou Y,Zhou M,Xiang B,Li X,Yang J,Xiong W,Li G,Zeng Z

Fri Aug 21 00:00:00 UTC 2015

Overexpression of RNF146 in non-small cell lung cancer enhances proliferation and invasion of tumors through the Wnt/β-catenin signaling pathway.

PloS one

Gao Y,Song C,Hui L,Li CY,Wang J,Tian Y,Han X,Chen Y,Tian DL,Qiu X,Wang E

Wed Sep 17 00:00:00 UTC 2014

Overexpression of RNF146 in non-small cell lung cancer enhances proliferation and invasion of tumors through the Wnt/β-catenin signaling pathway.

PloS one

Gao Y,Song C,Hui L,Li CY,Wang J,Tian Y,Han X,Chen Y,Tian DL,Qiu X,Wang E

Wed Sep 17 00:00:00 UTC 2014

Bioinformatics

Protein Aliases: aplysia ras-related homolog 9 (RhoC); AR ARHC; h9; MGC1448; MGC61427; oncogene RHO H9; ras homolog 9 (RhoC); ras homolog gene family, member C; RAS-related homolog 9; Rho; Rho cDNA clone 9; RHO MGC1448; Rho-related GTP-binding protein RhoC; rhoC GTPase; SIG-61; Silica-induced gene 61 protein; small GTP binding protein RhoC

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Gene Aliases: AI324259; ARH9; ARHC; H9; RHOC; RHOH9

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UniProt ID: (Human) P08134, (Mouse) Q62159

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Entrez Gene ID: (Human) 389, (Mouse) 11853, (Rat) 295342

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Function(s)

signal transducer activity protein binding GTP binding nucleotide binding small GTPase

Process(es)

cytokinesis small GTPase mediated signal transduction positive regulation of I-kappaB kinase/NF-kappaB signaling apical junction assembly wound healing, spreading of cells regulation of small GTPase mediated signal transduction positive regulation of lipase activity skeletal muscle satellite cell migration signal transduction

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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RHOC Polyclonal Antibody

RHOC Antibody (10632-1-AP) in WB

Product Details

10632-1-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Miscellaneous PubMed (Misc)

Not applicable (N/A)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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