PA1-29540 detects SFRP1 from human samples.
PA1-29540 has been successfully used in Western blot applications.
The PA1-29540 immunogen is: Synthetic peptide: IGPYQSGRFYTKC, corresponding to amino acids 42 - 53 of Human SFRP1.
This gene encodes a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. Members of this family act as soluble modulators of Wnt signaling; epigenetic silencing of SFRP genes leads to deregulated activation of the Wnt-pathway which is associated with cancer. This gene may also be involved in determining the polarity of photoreceptor cells in the retina.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: frizzled-related protein; FRP; FRP-1; FRP1; FrzA; SARP-2; SARP2; Secreted apoptosis-related protein 2; Secreted frizzled-related protein 1; secreted frizzled-related sequence protein 1; sFRP-1
Gene Aliases: 2210415K03Rik; AW011917; AW107218; AW742929; FRP; FRP-1; FRP1; FrzA; SARP2; sFRP-1; SFRP1