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Proteintech
SQLE Polyclonal Antibody, CoraLite® Plus 488
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Product Details
CL488-12544
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
SQLE fusion protein Ag3266
Conjugate
Excitation/Emission Max
493/522 nm
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 0.5% BSA, 50% glycerol
Contains
0.05% ProClin 300
Storage conditions
-20°C, store in dark
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: SRDGRKVTV IERDLKEPDR IVGEFLQPGG YHVLKDLGLG DTVEGLDAQV VNGYMIHDQE SKSEVQIPYP LSENNQVQSG RAFHHGRFIM SLRKAAMAEP NAKFIEGVVL QLLEEDDVVM GVQYKDKETG DIKELHAPLT VVADGLFSKF RKSLVSNKVS VSSHFVGFLM KNAPQFKANH AELILANPSP VLIYQISSSE TRVLVDIRGE MPRNLREYMV EKIYPQIPDH LKEPFLEATD NSHLRSMPAS FLPPSSVKKR GVLLLGDAYN MRHPLTGGGM TVAFKDIKLW RKLLKGIPDL YDDAAIFEAK KSFYWARKTS HSFVVNILAQ ALYELFSATD DSLHQLRKAC FLYFKLGGEC VAGPVGL
Target Information
SQLE, also named as ERG1, SE and SM, belongs to the squalene monooxygenase family. It catalyzes the first oxygenation step in cholesterol synthesis, acting on squalene before cyclization into the basic steroid structure. SQLE may serve as a flux-controlling enzyme beyond 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGR, considered as rate limiting). It is also post translationally regulated by cholesterol-dependent proteasomal degradation. The MW of SQLE is about 64 kDa.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: FLJ30795; SE; Squalene epoxidase; Squalene monooxygenase
Gene Aliases: AI323792; ERG1; SQLE
UniProt ID: (Human) Q14534, (Mouse) P52019, (Rat) P52020
Entrez Gene ID: (Human) 6713, (Mouse) 20775, (Rat) 29230
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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