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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • STEAP2 Antibodies

          Proteintech

          STEAP2 Polyclonal Antibody

          View all (7) STEAP2 antibodies

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          Cite STEAP2 Polyclonal Antibody

          • Antibody Testing Data (3)
          STEAP2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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          STEAP2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.

          FIGURE: 1 / 3

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          STEAP2 Antibody (24804-1-AP) in IHC (P)

          Immunohistochemical analysis of paraffin-embedded human colon cancer tissue slide using 24804-1-AP (STEAP2 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          STEAP2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          STEAP2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          STEAP2 Antibody in Western Blot (WB)
          STEAP2 Polyclonal Antibody

          Product Details

          24804-1-AP

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:800-1:1,000
          -

          Immunohistochemistry (Paraffin) (IHC (P))

          1:50-1:500
          -

          ELISA (ELISA)

          Assay-dependent
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          STEAP2 fusion protein Ag20293
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.55 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.3, with 50% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          -20°C

          Shipping conditions

          Wet ice

          Product Specific Information

          Immunogen sequence: QLGPKDASRQ VYICSNNIQA RQQVIELARQ LNFIPIDLGS LSSAREIENL PLRLFTLWRG PVVVAISLAT FFFLYSFVRD VIHPYARNQQ SDFYKIPIEI VNKTLPIVAI T

          Target Information

          The six-transmembrane epithelial antigen of prostate 2 (STEAP2) is a member of a family of metalloreductases identified as cell-surface antigens in prostate tissue. Similar to two other members of the STEAP family (STEAP 3 and STEAP4), STEAP2 promotes both iron and copper reduction. STEAP2 expression in transfected cells also correlated with iron or copper uptake, suggesting that the STEAP family of proteins may function to stimulate iron and copper uptake. STEAP2 is widely expressed in many tissues in the plasma membrane, but is most highly expressed in prostate. At least three isoforms of STEAP2 are known to exist.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: Metalloreductase STEAP2; prostate cancer associated protein 1; Prostate cancer-associated protein 1; Protein up-regulated in metastatic prostate cancer; protein upregulated in metastatic prostate cancer; PUMPCn; six transmembrane epithelial antigen of prostate 2; six transmembrane epithelial antigen of the prostate 2; Six-transmembrane epithelial antigen of prostate 2; SixTransMembrane Protein of Prostate 1; STEAP family member 2, metalloreductase

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          Gene Aliases: IPCA1; PCANAP1; PUMPCn; STAMP1; STEAP2; STMP; UNQ6507/PRO23203

          View more View less

          UniProt ID: (Human) Q8NFT2

          View more View less

          Entrez Gene ID: (Human) 261729

          View more View less

          Function(s)
          transporter activity cupric reductase activity metal ion binding ferric-chelate reductase (NADPH) activity
          Process(es)
          Golgi to plasma membrane transport endocytosis response to hormone copper ion import regulated exocytosis iron ion homeostasis oxidation-reduction process ferric iron import into cell
          It has to be done as per old AB suggested Products section.
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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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          Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.

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