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Invitrogen
STEAP3 Polyclonal Antibody
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Product Details
PA5-62202
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
C. elegans
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human STEAP3. Recombinant protein control fragment (Product #RP-101206).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: PKRTARLFPS AAQVTFQEEA VSSPEVIFVA VFREHYSSLC SLSDQLAGKI LVDVSNPTEQ EHLQHRE
Highest antigen sequence identity to the following orthologs: Mouse - 93%, Rat - 91%.
Target Information
The six-transmembrane epithelial antigen of prostate 3 (STEAP3) is a member of a family of metalloreductases identified as cell-surface antigens in prostate tissue. Similar to two other members of the STEAP family (STEAP 2 and STEAP4), STEAP3 promotes both iron and copper reduction. STEAP3 is highly expressed in hematopoietic tissues and colocalizes with the transferrin endosome. Overexpression of STEAP3 stimulates iron reduction; mice lacking STEAP3 are deficient in erythroid ferrireductase activity, suggesting that STEAP3 is an endosomal ferrireductase required for transferrin-dependent iron uptake in erythroid cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: dudlin 2; Dudulin-2; hpHyde; hTSAP6; Metalloreductase STEAP3; pHyde; Six-transmembrane epithelial antigen of prostate 3; STEAP family member 3, metalloreductase; tumor suppressor pHyde; Tumor suppressor-activated pathway protein 6
Gene Aliases: AHMIO2; dudlin-2; dudulin-2; pHyde; STEAP3; STMP3; TSAP6
UniProt ID: (Human) Q658P3
Entrez Gene ID: (Human) 55240
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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