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Search Thermo Fisher Scientific
Proteintech
Applications | Tested Dilution | Publications |
---|---|---|
Western Blot (WB) |
1:1,000-1:6,000 | View 2 publications 2 publications |
Immunohistochemistry (Paraffin) (IHC (P)) |
1:50-1:500 | - |
Immunohistochemistry (PFA fixed) (IHC (PFA)) |
1:4,000 | - |
Immunocytochemistry (ICC/IF) |
- | View 1 publication 1 publication |
Product Specifications | |
---|---|
Species Reactivity |
Human, Mouse, Rat |
Published species |
Mouse, Rat |
Host/Isotype |
Mouse / IgG1 |
Class |
Monoclonal |
Type |
Antibody |
Clone |
2D3B5 |
Immunogen |
Syntaxin 1A / Syntaxin 1B Fusion Protein Ag10257 (1-263 aa encoded by BC062298) |
Conjugate |
Unconjugated
|
Form |
Liquid |
Concentration |
1 mg/mL |
Purification |
Protein G |
Storage buffer |
PBS, pH 7.3, with 50% glycerol |
Contains |
0.02% sodium azide |
Storage conditions |
-20°C |
Immunogen sequence: MKDRTQELR SAKDSDDEEE VVHVDRDHFM DEFFEQVEEI RGCIEKLSED VEQVKKQHSA ILAAPNPDEK TKQELEDLTA DIKKTANKVR SKLKAIEQSI EQEEGLNRSS ADLRIRKTQH STLSRKFVEV MTEYNATQSK YRDRCKDRIQ RQLEITGRTT TNEELEDMLE SGKLAIFTDD IKMDSQMTKQ ALNEIETRHN EIIKLETSIR ELHDMFVDMA MLVESQGEMI DRIEYNVEHS VDYVERAVSD TKKAVKYQSK ARRK (1-263 aa encoded by BC062298)
This gene encodes a member of the syntaxin superfamily. Syntaxins are nervous system-specific proteins implicated in the docking of synaptic vesicles with the presynaptic plasma membrane. Syntaxins possess a single C-terminal transmembrane domain, a SNARE domain, and an N-terminal regulatory domain. Syntaxins bind synaptotagmin in a calcium-dependent fashion and interact with voltage dependent calcium and potassium channels via the C-terminal H3 domain. This gene product is a key molecule in ion channel regulation and synaptic exocytosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: adipocyte; adiponectin; FP17469; HGNC:11433; Neuron-specific antigen HPC-1; P35A; P35B; Synaptotagmin-associated 35 kDa protein; syntaxin 1 a; syntaxin 1A (brain); syntaxin 1A (brain)-like; syntaxin 1B1; syntaxin 1B2; Syntaxin 2; syntaxin a/b; Syntaxin-1A; Syntaxin-1B; Syntaxin-1B1; Syntaxin-1B2
Gene Aliases: GEFSP9; HPC-1; P35-1; Sap; STX1; STX1A; STX1B; STX1B1; STX1B2; Stx1bl; Stx2; SYN1A; Syn1b
UniProt ID: (Human) Q16623, (Human) P61266, (Mouse) O35526, (Rat) P32851, (Mouse) P61264, (Rat) P61265
Entrez Gene ID: (Human) 6804, (Human) 112755, (Mouse) 20907, (Rat) 116470, (Mouse) 56216, (Rat) 24923
Molecular Function:
SNARE protein
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