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Product Details
PA5-34447
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A 19 amino acid synthetic peptide near the amino terminus of human TCTEX1D4
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS
Contains
0.02% sodium azide
Storage conditions
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2551799
Product Specific Information
A suggested positive control is mouse liver tissue lysate.
PA5-34447 can be used with blocking peptide PEP-1489.
Target Information
Dyneins are multi-subunit, high molecular weight ATPases that interact with microtubules to generate force by converting the chemical energy of ATP into the mechanical energy of movement. Cytoplasmic or axonemal Dynein is an approximately 12 subunit complex of two heavy chains, two intermediate chains to anchor Dynein to its cargo, four smaller intermediate chains and several light chains. It performs functions necessary for cell survival such as organelle transport and centrosome assembly. TCTEX1 is a cytoplasmic dynein light chain found in a complex with Na+ CP type X (SCN10A). TCTEX1D4, also called TCTEX2 beta, interacts with different members of the TGF-beta receptor family, and when overexpressed, inhibits TGF-beta signaling.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Dynein light chain Tctex-type 4; N22.1; novel Tctex-1 family domain-containing protein; Protein N22.1; Tctex-2-beta; Tctex1 domain-containing protein 4; tctex1 domain-containing protein 4-like; Tctex2 beta
Gene Aliases: 4833401D15Rik; DYNLT4; TCTEX1D4
UniProt ID: (Human) Q5JR98, (Mouse) Q8CDY7
Entrez Gene ID: (Rat) 102551208, (Human) 343521, (Mouse) 242646
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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