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Proteintech
UBE2T/HSPC150 Polyclonal Antibody
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Product Details
10105-2-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
UBE2T/HSPC150 Fusion Protein Ag0153 (1-197 aa encoded by BC004152)
Conjugate
Form
Liquid
Concentration
0.37 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MQRASRLKR ELHMLATEPP PGITCWQDKD QMDDLRAQIL GGANTPYEKG VFKLEVIIPE RYPFEPPQIR FLTPIYHPNI DSAGRICLDV LKLPPKGAWR PSLNIATVLT SIQLLMSEPN PDDPLMADIS SEFKYNKPAF LKNARQWTEK HARQKQKADE EEMLDNLPEA GDSRVHNSTQ KRKASQLVGI EKKFHPDV (1-197 aa encoded by BC004152)
Target Information
UBE2T is involved in the covalent conjugation of ubiquitin to proteins regulates diverse cellular pathways and proteins. Ubiquitin is transferred to a target protein through a concerted action of a ubiquitin-activating enzyme (E1), a ubiquitin-conjugating enzyme (E2), such as UBE2T, and a ubiquitin ligase (E3). UBE2T catalyzes the covalent attachment of ubiquitin to protein substrates. Functionally, UBE2T accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins, catalyzes monoubiquitination, is involved in mitomycin-C (MMC)-induced DNA repair, and catalyzES monoubiquitination of FANCD2, a key step in the DNA damage pathway. Defects in the UBE2T gene have been associated with Fanconi anemia of complementation group T.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Cell proliferation-inducing gene 50 protein; E2 ubiquitin-conjugating enzyme T; HSPC150 protein similar to ubiquitin-conjugating enzyme; Ubiquitin carrier protein T; ubiquitin conjugating enzyme E2T; Ubiquitin-conjugating enzyme E2 T; ubiquitin-conjugating enzyme E2T (putative); Ubiquitin-protein ligase T
Gene Aliases: FANCT; HSPC150; PIG50; UBE2T
UniProt ID: (Human) Q9NPD8
Entrez Gene ID: (Human) 29089
DNA repair
protein monoubiquitination
cellular response to DNA damage stimulus
protein K29-linked ubiquitination
interstrand cross-link repair
protein K27-linked ubiquitination
protein autoubiquitination
protein K63-linked ubiquitination
protein K48-linked ubiquitination
protein K11-linked ubiquitination
protein K6-linked ubiquitination
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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