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Proteintech
UHMK1 Polyclonal Antibody
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Product Details
11624-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
UHMK1 Fusion Protein Ag2204 (3-344 aa encoded by BC026046)
Conjugate
Form
Liquid
Concentration
0.13 mg/mL
Amount
19.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: GSGCAWGAE PPRFLEAFGR LWQVQSRLGS GSSASVYRVR CCGNPGSPPG ALKQFLPPGT TGAAASAAEY GFRKERAALE QLQGHRNIVT LYGVFTIHFS PNVPSRCLLL ELLDVSVSEL LLYSSHQGCS MWMIQHCARD VLEALAFLHH EGYVHADLKP RNILWSAENE CFKLIDFGLS FKEGNQDVKY IQTDGYRAPE AELQNCLAQA GLQSDTECTS AVDLWSLGII LLEMFSGMKL KHTVRSQEWK ANSSATIDHI FASKAVVNAA IPAYHLRDLI KSMLHDDPSR RIPAEMALCS PFFSIPFAPH IEDLVMLPTP VLRLLNVLDD DYLENEEEYE GLC (3-344 aa encoded by BC026046)
Target Information
Upon serum stimulation, KIS, a member of the Ser/Thr protein kinase family, phosphorylates CDKN1B/p27Kip1, thus controlling CDKN1B subcellular location and cell cycle progression in G1 phase. This protein, which contains 1 RRM (RNA recognition motif)domain, may be involved in trafficking and/or processing of RNA. KIS is widely expressed, with highest levels in skeletal muscle, kidney, placenta and peripheral blood leukocytes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: kinase interacting stathmin; kinase interacting with leukemia-associated gene (stathmin); Kinase interacting with stathmin; KIS protein kinase; P-CIP2; PAM COOH-terminal interactor protein 2; Serine/threonine-protein kinase Kist; U2AF homology motif (UHM) kinase 1; U2AF homology motif kinase 1; unnamed protein product
Gene Aliases: 4732477C12Rik; 4930500M09Rik; AA673513; AI449218; AU021979; KIS; KIST; P-CIP2; UHMK1
UniProt ID: (Human) Q8TAS1, (Mouse) P97343, (Rat) Q63285
Entrez Gene ID: (Human) 127933, (Mouse) 16589, (Rat) 246332
nucleotide binding
nucleic acid binding
RNA binding
protein kinase activity
protein serine/threonine kinase activity
protein binding
ATP binding
kinase activity
transferase activity
ribonucleoprotein complex binding
protein serine kinase activity
transferase activity, transferring phosphorus-containing groups
enzyme binding
non-receptor serine/threonine protein kinase
protein modifying enzyme
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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