Immunogen sequence: DISHTLPIAA SSSLDAHIRL WDLENGKQIK SIDAGPVDAW TLAFSPDSQY LATGTHVGKV NIFGVESGKK EYSLDTR
Highest antigen sequence identity to the following orthologs: Mouse - 97%, Rat - 96%.
SKI8 is a component of the PAF and SKI complex which is composed of SKI2, SKI3 and SKI8. These are involved in transcriptional regulation and events downstream of RNA synthesis. Interaction of the SKI complex with SKI7 links the SKI complex to the exosome in order to perform mRNA degradation.
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Protein Aliases: meiotic recombination protein REC14; Meiotic recombination REC14 protein homolog; recombination protein REC14; Ski8; SKI8 homolog; WD repeat-containing protein 61; WD repeat-containing protein 61, N-terminally processed
Gene Aliases: 2700038L12Rik; 2810418I05Rik; REC14; RGD1308228; SKI8; WDR61