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Proteintech
ZC3H12D Polyclonal Antibody
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Product Details
24991-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
ZC3H12D Fusion Protein Ag21770 (1-90 aa encoded by BC157832)
Conjugate
Form
Liquid
Concentration
0.32 mg/mL
Amount
48 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MEHPSKMEF FQKLGYDRED VLRVLGKLGE GALVNDVLQE LIRTGSRPGA LEHPAAPRLV PRGSCGVPDS AQRGPGTALE EDFRTLASSL R (1-90 aa encoded by BC157832)
Target Information
ZC3H12D, also known as MCPIP4, is a member of a family of novel CCCH-zinc finger proteins that includes ZC3H12A, a protein that is thought to be involved in macrophage activation, host immunity and inflammatory diseases. ZC3H12D is highly expressed in spleen, intestine, and colon. Similar to ZC3H12A and ZC3H12C, ZC3H12D expression in murine macrophages is also increased after treatment with lipopolysaccharide (LPS), although not to the same level as ZC3H12A. This pattern of expression was not duplicated in human-derived macrophages, suggesting it also may play a different role in host immunity and inflammatory response.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: MCP-induced protein 4; p34; Probable ribonuclease ZC3H12D; RP1-281H8.5; Transformed follicular lymphoma; tumor suppressor TFL; unnamed protein product; Zinc finger CCCH domain-containing protein 12D
Gene Aliases: C6orf95; dJ281H8.1; MCPIP4; p34; TFL; ZC3H12D
UniProt ID: (Human) A2A288
Entrez Gene ID: (Human) 340152
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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