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Product Details
20119-1-AP
| Applications | Tested Dilution | Publications |
|---|---|---|
Western Blot (WB) |
1:500-1:1,000 | - |
Immunohistochemistry (Paraffin) (IHC (P)) |
1:20-1:200 | - |
Immunocytochemistry (ICC/IF) |
1:10-1:100 | - |
| Product Specifications | |
|---|---|
Species Reactivity |
Human |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
ZCCHC11 Fusion Protein Ag13661 (1-275 aa encoded by BC048301) |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
0.63 mg/mL |
Purification |
Antigen affinity chromatography |
Storage buffer |
PBS, pH 7.3, with 50% glycerol |
Contains |
0.02% sodium azide |
Storage conditions |
-20°C |
Product Specific Information
Immunogen sequence: MEESKTLKS ENHEPKKNVI CEESKAVQVI GNQTLKARND KSVKEIENSS PNRNSSKKNK QNDICIEKTE VKSCKVNAAN LPGPKDLGLV LRDQSHCKAK KFPNSPVKAE KATISQAKSE KATSLQAIAE KSPKSPNSVK AEKASSYQMK SEKVPSSPAE AEKGPSLLLK DMRQKTELQQ IGKKIPSSFT SVDKVNIEAV GGEKCALQNS PRSQKQQTCT DNTGDSDDSA SGIEDVSDDL SKMKNDESNK ENSSEMDYLE NATVIDESAL TPEQRL (1-275 aa encoded by B C048301)
Target Information
WDR77 is a component of the 20S PRMT5-containing methyltransferase complex, which modifies specific arginines to dimethylarginines in several spliceosomal Sm proteins. This modification targets Sm proteins to the survival of motor neurons (SMN) complex for assembly into small nuclear ribonucleoprotein core particles (Friesen et al., 2002).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: PAP associated domain containing 3; RP23-406B13.1; Terminal uridylyltransferase 4; TUTase 4; Zinc finger CCHC domain-containing protein 11; zinc finger, CCHC domain containing 11
Gene Aliases: KIAA0191; PAPD3; TUT4; ZCCHC11
UniProt ID: (Human) Q5TAX3
Entrez Gene ID: (Human) 23318
Molecular Function:
nucleotidyltransferase
transferase
metabolite interconversion enzyme
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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