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This gene encodes a protein subunit of the coatomer complex associated with non-clathrin coated vesicles. The coatomer complex, also known as the coat protein complex 1, forms in the cytoplasm and is recruited to the Golgi by activated guanosine triphosphatases. Once at the Golgi membrane, the coatomer complex may assist in the movement of protein and lipid components back to the endoplasmic reticulum. Alternatively spliced transcript variants have been described.
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Protein Aliases: beta coat protein; Beta-coat protein; Beta-COP; coatomer protein complex, subunit beta 1; Coatomer subunit beta; DKFZp761K102; FLJ10341; FLJ46444; FLJ57957; receptor for activated C-kinase-2
Gene Aliases: 2610019B04Rik; COPB; COPB1; MSTP026; Rack2
UniProt ID: (Human) P53618, (Mouse) Q9JIF7, (Rat) P23514
Entrez Gene ID: (Human) 1315, (Mouse) 70349, (Rat) 114023
Molecular Function:
membrane traffic protein
vesicle coat protein
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