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Invitrogen
Human Norrin ELISA Kit
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Product Specifications
Analytical sensitivity
0.41 ng/mL
Assay range
0.41-100 ng/mL
Sample type/volume
Supernatant
50 µL
Serum
50 µL
Plasma
50 µL
Hands-on time
1 hr 20 min
Time-to-result
4 hr 45 min
Homogenous (no wash)
No
Interassay CV
<12%
Intraassay CV
<10%
Instrument
Absorbance Microplate Reader
Product size
96 Tests
Contents
Pre-coated 96 well plate
Standard
Assay Diluent concentrate
Biotinylated Detection Antibody
SAV-HRP
Wash Buffer
Chromogen
Stop Solution
Adhesive Plate Covers
Standard
Assay Diluent concentrate
Biotinylated Detection Antibody
SAV-HRP
Wash Buffer
Chromogen
Stop Solution
Adhesive Plate Covers
Shipping conditions
Wet ice
Storage
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C
Protein name
NDP
Species (tested)
Human
Detector antibody conjugate
Biotin
Label or dye
HRP
About This Kit
Human Norrin quantitates human Norrin in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human Norrin.
Target information
NDP (Norrie disease protein), also known as norrin, is a secreted signaling protein encoded by the NDP gene that activates the canonical Wnt/β-catenin pathway by binding the Frizzled-4 (FZD4)/LRP5 receptor complex. It plays an essential role in retinal vascular development, maintenance of the blood-retina barrier, and inner ear vascularization. Loss-of-function variants in NDP cause Norrie disease and can also contribute to familial exudative vitreoretinopathy (FEVR).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Gene aliases : EVR2, FEVR, ND
Gene ID : (Human) 4693
Gene symbol : NDP
Protein Aliases : NDP, norrin cystine knot growth factor, Norrie disease (pseudoglioma), norrie disease protein, unnamed protein product, X-linked exudative vitreoretinopathy 2 protein
UniProt ID (Human) Q00604
Performance Guarantee
If an Invitrogen™ immunoassay doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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