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TAF1 Polyclonal Antibody

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TAF1 Polyclonal Antibody

Product Details

600-401-995

Applications
Tested Dilution
Publications

Western Blot (WB)

1:100-1:2,000
-

Immunohistochemistry (Paraffin) (IHC (P))

10 µg/mL
-

ELISA (ELISA)

1:150,000-1:300,000
-

Immunoprecipitation (IP)

Assay-dependent
-

ChIP assay (ChIP)

Assay-dependent
-
Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to amino acids near the carboxyl terminus of human TAF1.
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.1 mg/mL

Purification

Affinity chromatography

Storage buffer

0.02M potassium phosphate, pH 7.2, with 0.15M NaCl

Contains

0.01% sodium azide

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Directed against human TAF1 protein. A BLAST analysis was used to suggest cross-reactivity with TAF1 protein from human, mouse and rat based on 100% homology with the immunizing sequence. Reactivity against homologues from other sources is not known.

Target Information

3-Phosphoglycerate dehydrogenase (PHGDH; EC 1.1.1.95) catalyzes the transition of 3-phosphoglycerate into 3-phosphohydroxypyruvate, which is the first and rate-limiting step in the phosphorylated pathway of serine biosynthesis, using NAD+/NADH as a cofactor.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: Cell cycle gene 1 protein; cell cycle, G1 phase defect; complementation of cell cycle block, G1-to-S; p250; TAF(II)250; TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa; TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, neuron specific isoform; TBP-associated factor 250 kDa; transcription factor TFIID p250 polypeptide; Transcription initiation factor TFIID 250 kDa subunit; Transcription initiation factor TFIID subunit 1

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Gene Aliases: AU015687; B430306D02Rik; BA2R; Ccg-1; CCG1; CCGS; DYT3; DYT3/TAF1; KAT4; MRXS33; N-TAF1; NSCL2; OF; P250; RGD1562050; TAF(II)250; TAF1; TAF2A; TAFII-250; TAFII250; XDP

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UniProt ID: (Human) P21675, (Mouse) Q80UV9

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Entrez Gene ID: (Human) 6872, (Mouse) 270627, (Rat) 317256

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Function(s)
nucleotide binding RNA polymerase II core promoter sequence-specific DNA binding RNA polymerase II general transcription initiation factor binding transcription factor activity, core RNA polymerase I binding p53 binding DNA binding histone acetyltransferase activity protein kinase activity protein serine/threonine kinase activity protein binding ATP binding obsolete general RNA polymerase II transcription factor activity kinase activity transferase activity transferase activity, transferring acyl groups ligand-dependent nuclear receptor binding TBP-class protein binding sequence-specific DNA binding protein heterodimerization activity H3K27me3 modified histone binding RNA polymerase II sequence-specific DNA binding transcription factor binding ubiquitin conjugating enzyme activity peptide-lysine-N-acetyltransferase activity protein serine kinase activity histone H4K16ac reader activity transcription regulator inhibitor activity histone reader activity acetyl-CoA binding transcription coactivator activity transcription factor binding lysine-acetylated histone binding molecular_function general transcription factor
Process(es)
negative regulation of transcription from RNA polymerase II promoter protein polyubiquitination chromatin organization chromatin remodeling DNA-templated transcription, initiation transcription initiation from RNA polymerase I promoter transcription from RNA polymerase II promoter transcription initiation from RNA polymerase II promoter ubiquitin-dependent protein catabolic process cellular response to DNA damage stimulus negative regulation of gene expression midbrain development positive regulation of proteasomal ubiquitin-dependent protein catabolic process cellular response to UV mRNA transcription from RNA polymerase II promoter positive regulation of transcription from RNA polymerase II promoter protein autophosphorylation protein stabilization RNA polymerase II transcriptional preinitiation complex assembly positive regulation of transcription initiation from RNA polymerase II promoter cellular response to ATP positive regulation of androgen receptor signaling pathway regulation of signal transduction by p53 class mediator negative regulation of signal transduction by p53 class mediator regulation of cell cycle G1/S phase transition negative regulation of protein autoubiquitination negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process transcription, DNA-templated regulation of transcription, DNA-templated cell cycle phosphorylation histone acetylation peptidyl-serine phosphorylation peptidyl-threonine phosphorylation response to drug
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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