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Proteintech
Apolipoprotein A II Monoclonal Antibody (1G1A2)
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Product Details
66773-1-IG
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2b
Class
Monoclonal
Type
Antibody
Clone
1G1A2
Immunogen
Apolipoprotein A II Fusion Protein Ag9863 (1-100 aa encoded by BC005282)
Conjugate
Form
Liquid
Concentration
0.8 mg/mL
Amount
120 µg
Purification
Protein A
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MKLLAATVL LLTICSLEGA LVRRQAKEPC VESLVSQYFQ TVTDYGKDLM EKVKSPELQA EAKSYFEKSK EQLTPLIKKA GTELVNFLSY FVELGTQPAT Q (1-100 aa encoded by BC005282)
Target Information
At least 9 distinct polymorphic forms of apolipoproteins are known. The apolipoproteins act as stabilizers of the intact lipoprotein particles. Quantitative measurements of HDL, LDL, and VLDL particles of human serum are often used to estimate an individual's relative risk of coronary heart disease. In addition, quantitative immunological measurements of certain apolipoproteins ( especially A-1 and B) have been suggested to be more accurate estimators of coronary heart disease that measurements of lipoprotein particles (especially HDL and LDL). The apolipoproteins are derived from human plasma by density gradient ultracentrifugation and HPLC.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: APO A2; Apo-AII; Apolipoprotein; Apolipoprotein A-II; Apolipoprotein A2; Apolipoprotein AII; unnamed protein product
Gene Aliases: Apo-AII; ApoA-II; APOA2; apoAII
UniProt ID: (Human) P02652
Entrez Gene ID: (Human) 336
receptor binding
lipid transporter activity
protein binding
phospholipid binding
high-density lipoprotein particle binding
lipid binding
cholesterol binding
enzyme binding
heat shock protein binding
phosphatidylcholine binding
apolipoprotein receptor binding
protein homodimerization activity
protein heterodimerization activity
receptor agonist activity
lipase inhibitor activity
phosphatidylcholine-sterol O-acyltransferase activator activity
high-density lipoprotein particle receptor binding
intermembrane cholesterol transfer activity
negative regulation of cytokine production involved in immune response
triglyceride metabolic process
phosphatidylcholine biosynthetic process
lipid transport
signal transduction
cholesterol metabolic process
phospholipid catabolic process
response to glucose
negative regulation of very-low-density lipoprotein particle remodeling
protein oxidation
peptidyl-methionine modification
regulation of intestinal cholesterol absorption
cholesterol transport
regulation of protein stability
negative regulation of cholesterol transport
positive regulation of interleukin-8 production
cholesterol efflux
phospholipid efflux
triglyceride-rich lipoprotein particle remodeling
low-density lipoprotein particle remodeling
high-density lipoprotein particle remodeling
high-density lipoprotein particle assembly
high-density lipoprotein particle clearance
lipoprotein metabolic process
cholesterol homeostasis
reverse cholesterol transport
diacylglycerol catabolic process
positive regulation of phagocytosis
protein stabilization
negative regulation of lipid catabolic process
positive regulation of lipid catabolic process
negative regulation of cholesterol import
cellular response to lipoprotein particle stimulus
cellular response to beta-amyloid
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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