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Abnova
ING1 Monoclonal Antibody (2F9)
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Product Details
H00003621-M05
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgM, kappa
Class
Monoclonal
Type
Antibody
Clone
2F9
Immunogen
ING1 (NP_937862.1, 41 a.a. approximately 140 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Form
Liquid
Concentration
See Label
Amount
50 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Sequence of this protein is as follows: DAKYQEILKE LDECYERFSR ETDGAQKRRM LHCVQRALIR SQELGDEKIQ IVSQMVELVE NRTRQVDSHV ELFEAQQELG DTAGNSGKAG ADRPKGEAAA
Target Information
This gene encodes a tumor suppressor protein that can induce cell growth arrest and apoptosis. The encoded protein is a nuclear protein that physically interacts with the tumor suppressor protein TP53 and is a component of the p53 signaling pathway. Reduced expression and rearrangement of this gene have been detected in various cancers. Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: growth inhibitor ING1; growth inhibitor; tumor suppressor candidate; growth inhibitory protein ING1; Inhibitor of growth protein 1; p33ING; p33ING1; tumor suppressor ING1; unnamed protein product
Gene Aliases: ING1; p24ING1c; p33; p33ING1; p33ING1b; p47; p47ING1a
UniProt ID: (Human) Q9UK53
Entrez Gene ID: (Human) 3621
negative regulation of transcription from RNA polymerase II promoter
chromatin organization
protein import into nucleus
negative regulation of cell proliferation
negative regulation of cell growth
negative regulation of cell migration
negative regulation of transforming growth factor beta receptor signaling pathway
regulation of programmed cell death
positive regulation of transcription, DNA-templated
negative regulation of stem cell population maintenance
positive regulation of stem cell population maintenance
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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