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Invitrogen
MCCC2 Monoclonal Antibody (2B3)
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.jpg?time=20240507 "MCCC2 Antibody in Immunohistochemistry (PFA fixed) (IHC (PFA))")
.jpg?time=20240507)
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
.jpg?time=20240507?time=20240507 "MCCC2 Antibody (MA5-22463) in IHC (PFA)")
Product Details
MA5-22463
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1, kappa
Class
Monoclonal
Type
Antibody
Clone
2B3
Immunogen
MCCC2 (NP_071415, 456 a.a. ~ 563 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.5 mg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Peptide Sequence: AYSPRFLYIW PNARISVMGG EQAANVLATI TKDQRAREGK QFSSADEAAL KEPIIKKFEE EGNPYYSSAR VWDDGIIDPA DTRLVLGLSF SAALNAPIEK TDFGIFRM
Target Information
COX3 is a multi-pass membrane protein. It belongs to the cytochrome c oxidase subunit 3 family. Defects in COX3 are a cause of Leber hereditary optic neuropathy (LHON) and cytochrome c oxidase deficiency (COX deficiency). Defects in MT-CO3 are also found in mitochondrial encephalomyopathy with lactic acidosis and stroke-like episodes (MELAS) syndrome and recurrent myoglobinuria.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 3-methylcrotonyl-CoA carboxylase 2; 3-methylcrotonyl-CoA carboxylase non-biotin-containing subunit; 3-methylcrotonyl-CoA:carbon dioxide ligase subunit beta; biotin carboxylase; MCCase subunit beta; meth; methylcrotonoyl-CoA carboxylase 2 (beta); methylcrotonoyl-CoA carboxylase 2 (beta) isoform MCCC2_1; methylcrotonoyl-CoA carboxylase 2 (beta) isoform MCCC2_2; methylcrotonoyl-Coenzyme A carboxylase 2 (beta); non-biotin containing subunit of 3-methylcrotonyl-CoA carboxylase; testicular secretory protein Li 29; unnamed protein product
Gene Aliases: MCCB; MCCCbeta
UniProt ID: (Human) Q9HCC0
Entrez Gene ID: (Human) 64087
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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