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Invitrogen
RSK2 Recombinant Rabbit Monoclonal Antibody (23GB1530)
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FIGURE: 1 / 3
RSK2 Antibody (MA5-52592) in ICC/IF
Immunocytochemistry analysis of RSK2 in HepG2 cells. Nuclei were stained blue with DAPI; RSK2 recombinant monoclonal antibody (Product # MA5-52592) with a dilution of 1:1,000 was stained magenta with Alexa Fluor 647. Images were taken using Leica stellaris 5. Protein abundance based on laser Intensity and smart gain: Medium. Scale bar: 20 μm.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
MA5-52592
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293F
Class
Recombinant Monoclonal
Type
Antibody
Clone
23GB1530
Immunogen
A synthesized peptide derived from human RSK2/RPS6KA3 (670-700AA).
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.3 mg/mL
Amount
30 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
RPS6KA3 (RSK2) is a serine/threonine kinase that modulates many cellular processes including transcription, adhesion, growth, survival, and proliferation. RPS6KA3 contains 2 non-identical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Mutations in the gene have been associated with Coffin-Lowry syndrome (CLS).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 90 kDa ribosomal protein S6 kinase 3; epididymis secretory sperm binding protein; insulin-stimulated protein kinase 1; MAP kinase-activated protein kinase 1b; MAPK-activated protein kinase 1b; MAPKAP kinase 1b; MAPKAPK-1b; p90-RSK 3; ribosomal protein S6 kinase 2; ribosomal protein S6 kinase polypeptide 3; ribosomal protein S6 kinase, 90kDa, polypeptide 3; ribosomal S6 kinase 2; RPS6KA3; RSK-2; S6K-alpha-3; serine/threonine protein kinase RSK2; ribosomal protein S6 alpha 3; unnamed protein product
Gene Aliases: CLS; HU-3; ISPK-1; MAPKAPK-1b; MAPKAPK1B; MPK-9; MRX19; p90-RSK2; p90RSK3; pp90RSK2; RGD1563860; RSK; RSK2; S6K-alpha3; XLID19
UniProt ID: (Human) P51812, (Mouse) P18654
Entrez Gene ID: (Human) 6197, (Rat) 501560, (Mouse) 110651
toll-like receptor signaling pathway
biological_process
response to lipopolysaccharide
intracellular signal transduction
TORC1 signaling
negative regulation of apoptotic process
positive regulation of transcription from RNA polymerase II promoter
skeletal system development
regulation of transcription, DNA-templated
signal transduction
chemical synaptic transmission
central nervous system development
positive regulation of cell growth
regulation of translation in response to stress
positive regulation of cell differentiation
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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