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Invitrogen
ROBO2 Polyclonal Antibody
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Product Details
PA5-144712
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence. Antigen range: 1168-1309. Recombinant protein control fragment (Product #RP-109728).
Conjugate
Form
Liquid
Concentration
0.05 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: HLDELTRAYQ FDIAKQTWHI QSNNQPPQPP VPPLGYVSGA LISDLETDVA DDDADDEEEA LEIPRPLRAL DQTPGSSMDN LDSSVTGKAF TSSQRPRPTS PFSTDSNTSA ALSQSQRPRP TKKHKGGRMD QQPALPHRRE GM
Antigen sequence identity: Mouse 92%; Rat 92%
Target Information
ROBO2 belongs to the ROBO family, part of the immunoglobulin superfamily proteins that are highly conserved from fly to human. ROBO2 is a receptor for SLIT2, molecules known to function in axon guidance and cell migration. Defects in this gene are the cause of vesicoureteral reflux type 2. Alternatively spliced transcript variants encoding different isoforms have been described for ROBO2.This gene belongs to the ROBO family, part of the immunoglobulin superfamily proteins that are highly conserved from fly to human. The encoded protein is a receptor for SLIT2, molecules known to function in axon guidance and cell migration. Defects in this gene are the cause of vesicoureteral reflux type 2. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: H-Robo2; roundabout axon guidance receptor-like 2 isoform a; roundabout axon guidance receptor-like 2 isoform b; Roundabout homolog 2; roundabout, axon guidance receptor, homolog 2; unnamed protein product
Gene Aliases: KIAA1568; ROBO2; SAX3
UniProt ID: (Human) Q9HCK4
Entrez Gene ID: (Human) 6092
metanephros development
ureteric bud development
heart induction
outflow tract septum morphogenesis
aortic valve morphogenesis
pulmonary valve morphogenesis
endocardial cushion formation
chemotaxis
homophilic cell adhesion via plasma membrane adhesion molecules
nervous system development
axon guidance
central nervous system development
brain development
axon midline choice point recognition
olfactory bulb interneuron development
cell differentiation
retinal ganglion cell axon guidance
cellular response to hormone stimulus
tube development
aorta development
positive regulation of Notch signaling pathway
positive regulation of axonogenesis
negative regulation of negative chemotaxis
negative regulation of synapse assembly
ventricular septum morphogenesis
apoptotic process involved in luteolysis
cell-cell adhesion
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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