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Invitrogen
GAS6 Polyclonal Antibody
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Product Details
PA5-52539
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human GAS6. Recombinant protein control fragment (Product #RP-102272).
Conjugate
Form
Liquid
Concentration
0.4 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: STWEVEVVAH IRPAADTGVL FALWAPDLRA VPLSVALVDY HSTKKLKKQL VVLAVEHTAL ALMEIKVCDG QEHVVTVSLR DGEATLEVDG TRGQSEVSAA QLQERLAVLE RHLRSPVLTF AGGLPDVPVT S
Highest antigen sequence identity to the following orthologs: Mouse - 76%, Rat - 79%.
Target Information
This gene product is a gamma-carboxyglutamic acid (Gla)-containing protein thought to be involved in the stimulation of cell proliferation, and may play a role in thrombosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: AXL receptor tyrosine kinase ligand; AXL stimulatory factor; GAS-6; growth arrest-specific 6; Growth arrest-specific protein 6
Gene Aliases: AXLLG; AXSF; GAS6
UniProt ID: (Human) Q14393
Entrez Gene ID: (Human) 2621
phosphatidylserine binding
receptor binding
voltage-gated calcium channel activity
calcium ion binding
protein binding
protein tyrosine kinase activator activity
receptor tyrosine kinase binding
cysteine-type endopeptidase inhibitor activity involved in apoptotic process
receptor agonist activity
binding, bridging
extracellular matrix protein
neuron migration
positive regulation of protein phosphorylation
positive regulation of cytokine-mediated signaling pathway
platelet degranulation
positive regulation of glomerular filtration
signal peptide processing
protein phosphorylation
ER to Golgi vesicle-mediated transport
phagocytosis
apoptotic process
cell cycle arrest
cell adhesion
signal transduction
enzyme linked receptor protein signaling pathway
cell proliferation
cellular response to starvation
positive regulation of gene expression
negative regulation of tumor necrosis factor-mediated signaling pathway
macrophage cytokine production
cell migration
peptidyl-serine phosphorylation
fusion of virus membrane with host plasma membrane
viral genome replication
platelet activation
organ regeneration
cell-substrate adhesion
positive regulation of TOR signaling
activation of protein kinase B activity
negative regulation of interferon-gamma production
negative regulation of interleukin-6 production
negative regulation of tumor necrosis factor production
positive regulation of natural killer cell differentiation
positive regulation of peptidyl-serine phosphorylation
negative regulation of protein import into nucleus, translocation
cellular response to interferon-alpha
cellular response to drug
B cell chemotaxis
regulation of growth
negative regulation of apoptotic process
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
apoptotic cell clearance
negative regulation of sequence-specific DNA binding transcription factor activity
protein kinase B signaling
positive regulation of protein kinase activity
negative regulation of transcription, DNA-templated
viral entry into host cell
receptor-mediated virion attachment to host cell
positive regulation of protein export from nucleus
positive regulation of fibroblast proliferation
negative regulation of interleukin-1 secretion
positive regulation of phagocytosis
leukocyte migration
positive regulation of protein kinase B signaling
positive regulation of protein tyrosine kinase activity
negative regulation of biomineral tissue development
positive regulation of ERK1 and ERK2 cascade
platelet aggregation
calcium ion transmembrane transport
cellular response to vitamin K
cellular response to glucose stimulus
cellular response to growth factor stimulus
protein targeting to plasma membrane
extracellular matrix assembly
dendritic cell differentiation
hematopoietic stem cell migration to bone marrow
negative regulation of oligodendrocyte apoptotic process
negative regulation of interleukin-6 secretion
negative regulation of fibroblast apoptotic process
negative regulation of endothelial cell apoptotic process
positive regulation of dendritic cell chemotaxis
negative regulation of renal albumin absorption
negative regulation of dendritic cell apoptotic process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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