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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • SON Antibodies

          Invitrogen

          SON Polyclonal Antibody

          1 Reference
          View all (8) SON antibodies

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          Cite SON Polyclonal Antibody

          • Antibody Testing Data (1)
          SON Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.
          SON Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.

          FIGURE: 1 / 1

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          SON Antibody (PA5-65108) in ICC/IF

          Immunofluorescent staining of SON in human cell line A-431 shows localization to nuclear speckles. Samples were probed using a SON Polyclonal Antibody (Product # PA5-65108). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          SON Antibody in Immunocytochemistry (ICC/IF)
          SON Polyclonal Antibody

          Product Details

          PA5-65108

          Applications
          Tested Dilution
          Publications

          Immunocytochemistry (ICC/IF)

          0.25-2 µg/mL
          View 1 publication 1 publication
          Product Specifications

          Species Reactivity

          Human

          Published species

          Human

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Recombinant Human SON. Recombinant protein control fragment (Product #RP-105864).
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.10 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.2, with 40% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2662628

          Product Specific Information

          Immunogen sequence: PVAKVLEPSET LVVSSETPTE VYPEPSTSTT MDFPESSAIE ALRLPEQPVD VPSEIADSSM TRPQELPELP KTTALE

          Highest antigen sequence identity to the following orthologs - mouse 77%, rat 77%.

          Target Information

          The protein encoded by this gene binds to a specific DNA sequence upstream of the upstream regulatory sequence of the core promoter and second enhancer of human hepatitis B virus (HBV). Through this binding, it represses HBV core promoter activity, transcription of HBV genes, and production of HBV virions. The protein shows sequence similarities with other DNA-binding structural proteins such as gallin, oncoproteins of the MYC family, and the oncoprotein MOS. It may also be involved in protecting cells from apoptosis and in pre-mRNA splicing. Several transcript variants encoding different isoforms have been described for this gene, but the full-length nature of only two of them has been determined. [provided by RefSeq].

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          Bioinformatics

          Protein Aliases: BASS1; Bax antagonist selected in Saccharomyces 1; Negative regulatory element-binding protein; NRE-binding protein; Protein DBP-5; Protein SON; SON3

          View more View less

          Gene Aliases: BASS1; C21orf50; DBP-5; DBP5; HSPC310; HSPC312; KIAA1019; NREBP; SON; SON3

          View more View less

          UniProt ID: (Human) P18583

          View more View less

          Entrez Gene ID: (Human) 6651

          View more View less

          Function(s)
          nucleic acid binding DNA binding RNA binding protein binding poly(A) RNA binding RS domain binding RNA metabolism protein RNA processing factor RNA splicing factor nucleic acid metabolism protein
          Process(es)
          microtubule cytoskeleton organization mitotic cytokinesis mRNA processing RNA splicing negative regulation of apoptotic process regulation of mRNA splicing, via spliceosome regulation of cell cycle
          It has to be done as per old AB suggested Products section.
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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

          Learn more
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          We're here to help

          Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.

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