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Invitrogen
GOT1 Polyclonal Antibody
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Product Details
PA5-67252
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Human GOT1. Recombinant protein control fragment (Product #RP-105569).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: IGMFSFTGLNP KQVEYLVNEK HIYLLPSGRI NVSGLTTKNL DYVATSIHEA VTKIQ
Highest antigen sequence identity to the following orthologs - mouse 96%, rat 91%.
Target Information
GOT1 is a glutamic-oxaloacetic transaminase is a pyridoxal phosphate-dependent enzyme which exists in cytoplasmic and mitochondrial forms, GOT1 and GOT2, respectively. GOT plays a role in amino acid metabolism and the urea and tricarboxylic acid cycles. The two enzymes are homodimeric and show close homology.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: aspartate aminotransferase; aspartate aminotransferase 1; Aspartate aminotransferase, cytoplasmic; aspartate transaminase 1; cAspAT; cCAT; Cysteine aminotransferase, cytoplasmic; Cysteine transaminase, cytoplasmic; Glutamate oxaloacetate transaminase 1; glutamic-oxaloacetic transaminase 1, soluble; growth-inhibiting protein 18; testis secretory sperm-binding protein Li 196a; Transaminase A; unnamed protein product
Gene Aliases: AST; AST1; ASTQTL1; cAspAT; cCAT; GIG18; GOT1; SGOT
UniProt ID: (Human) P17174
Entrez Gene ID: (Human) 2805
gluconeogenesis
2-oxoglutarate metabolic process
oxaloacetate metabolic process
glycerol biosynthetic process
cellular amino acid metabolic process
aspartate metabolic process
aspartate biosynthetic process
aspartate catabolic process
glutamate metabolic process
Notch signaling pathway
cellular amino acid biosynthetic process
response to carbohydrate
glutamate catabolic process to aspartate
positive regulation of transforming growth factor beta receptor signaling pathway
cellular response to insulin stimulus
negative regulation of collagen biosynthetic process
response to immobilization stress
malate-aspartate shuttle
dicarboxylic acid metabolic process
response to cadmium ion
response to glucocorticoid
negative regulation of cytosolic calcium ion concentration
negative regulation of mitochondrial depolarization
fatty acid homeostasis
transdifferentiation
cellular response to mechanical stimulus
L-glutamate biosynthetic process
response to transition metal nanoparticle
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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