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Invitrogen
GOT2 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-82616
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human GOT2. Recombinant protein control fragment (Product #RP-91302).
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.1 mg/mL
Amount
10 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: GFASGDGDKD AWAVRHFIEQ GINVCLCQSY AKNMGLYGER VGAFTMVCKD ADEAKRVESQ LKILIRPMYS NPPLNGARIA AAILNTPDLR KQWLQEVKGM ADRIIGMRTQ LVSNLKKEGS THNWQHITDQ IGMFCFTGLK PEQVER
Highest antigen sequence indentity to the following orthologs: Mouse - 95%, Rat - 95%.
Target Information
GOT2 is a glutamic-oxaloacetic transaminase is a pyridoxal phosphate-dependent enzyme which exists in cytoplasmic and inner-membrane mitochondrial forms, GOT1 and GOT2, respectively. GOT plays a role in amino acid metabolism and the urea and tricarboxylic acid cycles. The two enzymes are homodimeric and show close homology.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: aspartate aminotransferase 2; aspartate aminotransferase precursor (2.6.1.1); aspartate aminotransferase precursor (EC 2.6.1.1); aspartate transaminase 2; FABP-1; FABPpm; fatty acid-binding protein; FLJ40994; glutamate oxaloacetate transaminase 2; glutamate oxaloacetate transaminase 2, mitochondrial; Glutamate oxaloacetate transaminase 2, mitochondrial (aspartate aminotransferase 2); glutamic oxaloacetic transaminase (EC 2.6.1.1); glutamic-oxaloacetic transaminase 2, mitochondrial; glutamic-oxaloacetic transaminase 2, mitochondrial (aspartate aminotransferase 2); kynurenine aminotransferase 4; kynurenine aminotransferase IV; kynurenine--oxoglutarate transaminase 4; kynurenine--oxoglutarate transaminase IV; mAspAT; mitochondrial aspartate aminotransferase; plasma membrane fatty acid binding protein; plasma membrane-associated fatty acid-binding protein; precytosolic aspartate aminotransferase (EC 2.6.1.1); transaminase A; unnamed protein product
Gene Aliases: ASPATA; DEE82; FABP-pm; Got-2; KAT4; KATIV; KYAT4; mAAT; mAspAT; mitAAT
UniProt ID: (Human) P00505, (Mouse) P05202, (Rat) P00507
Entrez Gene ID: (Human) 2806, (Mouse) 14719, (Rat) 25721
RNA binding
catalytic activity
L-aspartate:2-oxoglutarate aminotransferase activity
transaminase activity
kynurenine-oxoglutarate transaminase activity
pyridoxal phosphate binding
phospholipid binding
amino acid binding
enzyme binding
carboxylic acid binding
identical protein binding
(4S)-4-hydroxy-L-glutamate:2-oxoglutarate transaminase activity
2-oxoglutarate metabolic process
cellular amino acid metabolic process
aspartate metabolic process
aspartate catabolic process
glutamate metabolic process
glutamine catabolic process
fatty acid transport
4-hydroxyproline catabolic process
malate-aspartate shuttle
response to ethanol
L-asparagine biosynthetic process
oxaloacetate metabolic process
aspartate biosynthetic process
glutamate catabolic process
female pregnancy
lactation
response to muscle activity
response to insulin
dicarboxylic acid metabolic process
L-glutamate biosynthetic process
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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