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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: KSTAKWAASL ENLLEDPEGV KRFREFLKKE FSEENVLFWL ACEDFKKMQD KTQMQEKAKE IYMTFLSSKA SSQVNVEGQS RLNEKILEEP HPLMFQKLQD QI
Highest antigen sequence indentity to the following orthologs: Mouse - 92%, Rat - 93%.
RGS10 inhibits signal transduction by increasing the GTPASE activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. It associates specifically with the activated forms of the G protein subunits G(I)-ALPHA and G(Z)- alpha but fails to interact with the structurally and functionally distinct G(S)-alpha subunit. Activity on G(Z)-alpha is inhibited by palmitoylation of the G-protein.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Regulator of G-protein signaling 10; RGS10
Gene Aliases: RGS10
Entrez Gene ID: (Human) 6001
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