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Invitrogen

ThPOK Polyclonal Antibody

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ThPOK Polyclonal Antibody

Product Details

PA5-82901

Applications
Tested Dilution
Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:50
-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human ZBTB7B. Recombinant protein control fragment (Product #RP-89377).
3D Epitope / Immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Amount

10 µg

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2790057

Product Specific Information

Immunogen sequence: LLEFAYTATL TTSSANMPAV LQAARLLEIP CVIAACMEIL QGSGLEAPSP DEDDCERARQ YLEAFATATA SGVPNGEDSP PQVPLPPPPP PPPRPVARRS RKPRKAFLQT KG

Highest antigen sequence indentity to the following orthologs: Rat - 94%, Mouse - 94%.

Target Information

ZFP67 is an early growth response gene that encodes a zinc finger-containing transcription factor that binds to the promoter regions of type I collagen genes (e.g., COL1A1; MIM 120150) and has a role in development.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: DKFZp686G01254; hcKrox; Krueppel-related zinc finger protein cKrox; RP11-307C12.9; T-helper-inducing POZ/Krueppel-like factor; unnamed protein product; Zfp-67; zinc finger and BTB domain containing 15; Zinc finger and BTB domain-containing protein 15; Zinc finger and BTB domain-containing protein 7B; Zinc finger protein 67 homolog; Zinc finger protein 857B; Zinc finger protein Th-POK; zinc-finger transcription factor

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Gene Aliases: c-KROX; CKROX; hcKROX; THPOK; vGAF; ZBTB15; ZBTB7B; ZFP-67; ZFP67; ZNF857B

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UniProt ID: (Human) O15156

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Entrez Gene ID: (Human) 51043

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Function(s)
RNA polymerase II core promoter proximal region sequence-specific DNA binding RNA polymerase II transcription factor activity, sequence-specific DNA binding core promoter proximal region sequence-specific DNA binding bacterial-type RNA polymerase transcriptional repressor activity, sequence-specific DNA binding transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding DNA binding transcription factor activity, sequence-specific DNA binding protein binding zinc ion binding identical protein binding protein homodimerization activity histone deacetylase binding metal ion binding sequence-specific double-stranded DNA binding
Process(es)
negative regulation of transcription from RNA polymerase II promoter NK T cell differentiation regulation of transcription from RNA polymerase II promoter transcription from RNA polymerase II promoter ectoderm development lactation regulation of gene expression positive regulation of gene expression negative regulation of gene expression cell differentiation positive regulation of interleukin-17 production response to insulin positive regulation of CD4-positive, alpha-beta T cell differentiation regulation of CD8-positive, alpha-beta T cell differentiation negative regulation of CD8-positive, alpha-beta T cell differentiation regulation of T-helper cell differentiation positive regulation of transcription from RNA polymerase II promoter positive regulation of insulin receptor signaling pathway negative regulation of NK T cell proliferation positive regulation of brown fat cell differentiation positive regulation of cold-induced thermogenesis adaptive thermogenesis negative regulation of T-helper 17 cell differentiation positive regulation of SREBP signaling pathway
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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