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          • Primary Antibodies ›
          • Synapsin 1 Antibodies

          Invitrogen

          Phospho-Synapsin 1 (Ser9) Polyclonal Antibody

          View all (34) Synapsin 1 antibodies

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          Cite Phospho-Synapsin 1 (Ser9) Polyclonal Antibody

          Additional Information:
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          • Antibody Testing Data (2)
          Phospho-Synapsin 1 (Ser9) Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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          Phospho-Synapsin 1 (Ser9) Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.

          FIGURE: 1 / 2

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          Phospho-Synapsin 1 (Ser9) Antibody (PA5-104822) in IHC (P)

          Immunohistochemistry analysis of Phospho-Synapsin 1 (Ser9) in mouse brain tissue. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. Samples were incubated with Phospho-Synapsin 1 (Ser9) polyclonal antibody (Product # PA5-104822) using a dilution of 1:100 (4°C overnight) followed by HRP conjugated anti-Rabbit secondary antibody. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          View Product

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          Phospho-Synapsin 1 (Ser9) Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Phospho-Synapsin 1 (Ser9) Antibody in Western Blot (WB)

          Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.

          Phospho-Synapsin 1 (Ser9) Polyclonal Antibody

          Product Details

          PA5-104822

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500-1:2,000
          -

          Immunohistochemistry (Paraffin) (IHC (P))

          1:50-1:200
          -

          Immunocytochemistry (ICC/IF)

          1:100-1:500
          -
          Product Specifications

          Species Reactivity

          Human, Mouse, Rat

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          A synthesized peptide derived from human SYN1(Accession P17600), corresponding to amino acid residues around phosphorylated Ser9.
          3D Epitope / Immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          1 mg/mL

          Amount

          100 µg

          Purification

          sequential chromatography

          Storage buffer

          PBS, pH 7.4, with 50% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          -20°C

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2816295

          Product Specific Information

          Antibody detects endogenous levels of Synapsin I only when phosphorylated at Serine 9.

          Target Information

          SYN1 (synapsin 1) is a member of the synapsin gene family. Synapsins encode neuronal phosphoproteins that associate with the cytoplasmic surface of synaptic vesicles. Family members are characterized by common protein domains and are implicated in synaptogenesis and the modulation of neurotransmitter release, suggesting a potential role in several neuropsychiatric diseases. Synapsin 1 plays a role in regulation of axonogenesis and synaptogenesis. It serves as a substrate for several different protein kinases and phosphorylation may function in the regulation of this protein in the nerve terminal. Mutations in this gene may be associated with X-linked disorders with primary neuronal degeneration such as Rett syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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          Cite this product

          Bioinformatics

          Protein Aliases: Brain protein 4.1; synapsin 1; Synapsin I; Synapsin-1; truncated synapsin 1-S

          View more View less

          Gene Aliases: Syn-1; SYN1; Syn1-S

          View more View less

          UniProt ID: (Rat) P09951, (Mouse) O88935

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          Entrez Gene ID: (Rat) 24949, (Mouse) 20964

          View more View less

          Function(s)
          actin binding catalytic activity protein binding ATP binding protein kinase binding calcium-dependent protein binding protein dimerization activity membrane trafficking regulatory protein
          Process(es)
          neurotransmitter secretion metabolic process
          It has to be done as per old AB suggested Products section.

          Disclaimer

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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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