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OriGene
FABP5 Polyclonal Antibody
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FIGURE: 1 / 1
FABP5 Antibody (TA890007) in WB
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY FABP5 (RC201973, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with Rabbit anti. Positive lysates LY400560 (100 µg) and LC400560 (20 µg) can be purchased separately from OriGene.
Product Details
TA890007
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide conjugated to KLH derived from C terminal of Human FABP5.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS with 1% BSA, 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
FABP5 (fatty acid binding protein 5 (psoriasis-associated)) is a proteinthat in humans is encoded by theFABP5 gene, also known as PAFABP, EFABP, E-FABP, KFABP, PA-FABP, Epidermal-type fatty acid-binding protein, Fatty acid-binding protein 5, Psoriasis-associated fatty acid-binding protein homolog. It is a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. The PAFABP cDNA encodes a 135-amino acid protein with molecular weight 15,164. This gene encodes the fatty acid binding protein found in epidermal cells, and was first identified as being upregulated inpsoriasistissue. It is though that FABPs roles include fatty acid uptake, transport, and metabolism. Kaczocha et al. (2009) identifiedFABP5and FABP7 as cytosolic proteins that transport AEA from the plasma membrane to subcellular fatty acid amide hydrolase, where it is hydrolyzed and inactivated. FABP3 did not show this specific transport function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: E-FABP; E-FABPPAFABP; Epidermal-type fatty acid-binding protein; fatty acid binding protein 5 (psoriasis-associated); Fatty acid-binding protein 5; Fatty acid-binding protein, epidermal; PA-FABP; PA-FABPepidermal; Psoriasis-associated fatty acid-binding protein homolog; unnamed protein product
Gene Aliases: E-FABP; EFABP; FABP5; KFABP; PA-FABP; PAFABP
UniProt ID: (Human) Q01469
Entrez Gene ID: (Human) 2171
glucose metabolic process
lipid metabolic process
phosphatidylcholine biosynthetic process
lipid transport
epidermis development
negative regulation of glucose transport
fatty acid transport
long-chain fatty acid transport
regulation of prostaglandin biosynthetic process
positive regulation of peroxisome proliferator activated receptor signaling pathway
glucose homeostasis
regulation of sensory perception of pain
retrograde trans-synaptic signaling by endocannabinoid
regulation of retrograde trans-synaptic signaling by endocanabinoid
positive regulation of cold-induced thermogenesis
lipid transport across blood brain barrier
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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