Search
OriGene
AK4 Monoclonal Antibody (OTI3E1), TrueMAB™
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
FIGURE: 1 / 6
AK4 Antibody (TA502910S) in WB
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY AK4 (RC220572, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-AK4. Positive lysates LY402259 (100 µg) and LC402259 (20 µg) can be purchased separately from OriGene.
Product Details
TA502910S
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
OTI3E1
Immunogen
Full length human recombinant protein of human AK4 produced in HEK293T cell.
Conjugate
Form
Liquid
Concentration
0.68 mg/mL
Amount
20.4 µg
Purification
Affinity chromatography
Storage buffer
PBS with 1% BSA, 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
This gene encodes a member of the adenylate kinase family of enzymes. The encoded protein is localized to the mitochondrial matrix. Adenylate kinases regulate the adenine and guanine nucleotide compositions within a cell by catalyzing the reversible transfer of phosphate group among these nucleotides. Five isozymes of adenylate kinase have been identified in vertebrates. Expression of these isozymes is tissue-specific and developmentally regulated. A pseudogene for this gene has been located on chromosome 17. Three transcript variants encoding the same protein have been identified for this gene. Sequence alignment suggests that the gene defined by NM_013410, NM_203464, and NM_001005353 is located on chromosome 1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: Adenylate kinase 3-like; adenylate kinase 3-like 1; Adenylate kinase 4, mitochondrial; adenylate kinase isoenzyme 4, mitochondrial; AK3; ATP-AMP transphosphorylase; epididymis secretory sperm binding protein; GTP:AMP phosphotransferase AK4; GTP:AMP phosphotransferase AK4, mitochondrial; mitochondrial adenylate kinase-3; nucleoside-triphosphate-adenylate kinase; RP4-686B20.1; unnamed protein product
Gene Aliases: AK 4; AK3; AK3L1; AK3L2; AK4
UniProt ID: (Human) P27144
Entrez Gene ID: (Human) 205
nucleotide binding
adenylate kinase activity
nucleoside diphosphate kinase activity
protein binding
ATP binding
GTP binding
kinase activity
transferase activity
phosphotransferase activity, phosphate group as acceptor
nucleobase-containing compound kinase activity
CMP kinase activity
dCMP kinase activity
nucleoside triphosphate adenylate kinase activity
dAMP kinase activity
nucleoside phosphate kinase activity
regulation of oxidative phosphorylation
nucleobase-containing compound metabolic process
ADP biosynthetic process
nucleotide metabolic process
nucleoside monophosphate metabolic process
nucleoside triphosphate biosynthetic process
ribonucleoside diphosphate biosynthetic process
nucleobase-containing small molecule interconversion
AMP metabolic process
ATP metabolic process
GTP metabolic process
nucleoside monophosphate phosphorylation
cellular response to hypoxia
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support