Search
Invitrogen
AMPK gamma-2 Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
Product Details
38-4200
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide derived from the N-terminal region of the human AMPK-gamma-2 (5'-AMP-activated protein kinase, gamma-2subunit, PRKAG2) protein, which differs from mouse by one amino acid.
Conjugate
Form
Liquid
Concentration
0.25 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
0.1% sodium azide
Storage conditions
Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
AMP-activated protein kinase (AMPK) is a heterotrimeric protein composed of a catalytic alpha subunit, a noncatalytic beta subunit, and a noncatalytic regulatory gamma subunit. Various forms of each of these subunits exist, encoded by different genes. AMPK is an important energy-sensing enzyme that monitors cellular energy status and functions by inactivating key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This gene is a member of the AMPK gamma subunit family and encodes a protein with four cystathionine beta-synthase domains. Mutations in this gene have been associated with ventricular pre-excitation (Wolff-Parkinson-White syndrome), progressive conduction system disease and cardiac hypertrophy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: 5'-AMP-activated protein kinase subunit gamma-2; 5-AMP-activated protein kinase, gamma-2 subunit; ampk gamma; AMPK gamma-2 chain; AMPK gamma2; AMPK subunit gamma-2; epididymis secretory sperm binding protein; H91620p; OTTHUMP00000211956; protein kinase, AMP-activated, gamma 2 non-catalytic subunit; unnamed protein product
Gene Aliases: 2410051C13Rik; AAKG; AAKG2; AI854673; CMH6; H91620p; PRKAG2; WPWS
UniProt ID: (Human) Q9UGJ0, (Mouse) Q91WG5
Entrez Gene ID: (Human) 51422, (Mouse) 108099
nucleotide binding
AMP-activated protein kinase activity
cAMP-dependent protein kinase inhibitor activity
protein binding
ATP binding
cAMP-dependent protein kinase regulator activity
phosphorylase kinase regulator activity
AMP binding
protein kinase regulator activity
protein kinase binding
protein kinase activator activity
ADP binding
kinase modulator
glycogen metabolic process
regulation of glycolytic process
lipid metabolic process
fatty acid metabolic process
fatty acid biosynthetic process
ATP biosynthetic process
sterol biosynthetic process
regulation of fatty acid metabolic process
cellular response to nutrient levels
intracellular signal transduction
cellular response to glucose starvation
regulation of carbon utilization
positive regulation of gluconeogenesis
regulation of fatty acid oxidation
regulation of glucose import
regulation of cell cycle
protein phosphorylation
negative regulation of protein kinase activity
positive regulation of peptidyl-threonine phosphorylation
positive regulation of protein kinase activity
regulation of catalytic activity
negative regulation of protein serine/threonine kinase activity
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support