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Invitrogen
SARS-CoV-2 Spike Protein (RBD) Chimeric Recombinant Rabbit Monoclonal Antibody (T01KHuRb)
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FIGURE: 1 / 11
SARS-CoV-2 Spike Protein (RBD) Chimeric Antibody (703959) in ICC/IF
For Immunofluorescence analysis, HEK-293 cells were transfected with a vector encoding full length spike protein from SARS CoV2. Cells were fixed and permeabilized for detection of spike protein using Anti-SARS CoV2 Spike Protein RBD Recombinant Rabbit Chimera Monoclonal Antibody (Product # 703959) at a concentration of 5 µg/mL and labeled with Goat anti-Rabbit IgG (H+L) Highly Cross-Adsorbed Secondary Anti... View More
Product Details
703959
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Virus
Published species
Human,
Virus
Host/Isotype
Rabbit
/ IgG, kappa
Expression System
Expi293
Class
Recombinant Monoclonal
Type
Antibody
Clone
T01KHuRb
Immunogen
This antibody was developed using computationally derived variants of SARS-CoV antibody structures and is shown to bind Spike Protein S1 subunit (RBD) of SARS CoV2
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
0.09% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
Product Specific Information
This antibody has a human Fab containing a kappa light chain, and Rabbit Fc. It recognizes the RBD domain of SARS CoV2 Spike protein.
It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.
This antibody is not recommended for the Western blot application.
Target Information
SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2) also known as 2019-nCoV (2019 Novel Coronavirus) is a virus that causes illnesses ranging from the common cold symptoms to severe effects including death and respiratory distress. The CoV Spike (S) protein plays the most important roles in viral attachment, fusion and entry, and serves as a target for development of antibodies, entry inhibitors and vaccines. Of note is the Spike protein receptor-binding domain (RBD, S-RBD) in SARS-CoV-2 Spike protein which binds strongly to human and bat angiotensin-converting enzyme 2 (ACE2) receptors. SARS-CoV-2 RBD exhibits significantly higher binding affinity to ACE2 receptor than SARS-CoV RBD in comparison. S1 contains a receptor-binding domain (RBD) that can specifically bind to angiotensin-converting enzyme 2 (ACE2), the receptor on target cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Coronavirus; COVID; Covid 19; COVID-19; COVID19; SARS; SARS Coronavirus; SARS CoV; SARS CoV-2; SARS CoV2; SARS Spike Protein; SARS-CoV-2; SARS-CoV2
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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