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Bethyl Laboratories
NIF1 Polyclonal Antibody
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FIGURE: 1 / 2
NIF1 Antibody (A300-797A) in IHC (P)
Detection of human and mouse NIF1 by immunohistochemistry. Sample: FFPE section of human thyroid carcinoma (left) and mouse squamous cell carcinoma (right). Antibody: Affinity purified rabbit anti-NIF1 (Product # A300-797A) (Lot 1) used at a dilution of 1:5,000 (0.2 µg/mL). Detection: DAB.
Product Details
A300-797A
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Region between residue 300 and 350 of human NRC-Interacting Factor 1.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
tris citrate/phosphate, pH 7-8
Contains
0.09% sodium azide
Storage conditions
4°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Application Note: For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
Based on 100% sequence identity, this antibody is predicted to react with Rat
Target Information
Component or associated component of some histone methyltransferase complexes may regulate transcription through recruitment of those complexes on gene promoters. Enhances ligand-dependent transcriptional activation by nuclear hormone receptors. Plays an important role in neural progenitor cell proliferation and self-renewal through the regulation of specific genes involved brain development, including REST. Also controls the expression of genes involved in somatic development and regulates, for instance, lymphoblast proliferation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: NIF-1; NRC-interacting factor 1; nulcear protein; unnamed protein product; Zinc finger protein 335; zinc-finger/leucine-zipper co-transducer NIF1
Gene Aliases: 1810045J01Rik; MCPH10; NIF-1; NIF1; NIF2; Zfp335; ZNF335
UniProt ID: (Human) Q9H4Z2, (Mouse) A2A5K6
Entrez Gene ID: (Human) 63925, (Mouse) 329559
transcription regulatory region sequence-specific DNA binding
RNA polymerase II core promoter proximal region sequence-specific DNA binding
DNA binding
protein binding
zinc ion binding
metal ion binding
histone methyltransferase binding
RNA polymerase II core promoter sequence-specific DNA binding
nucleic acid binding
transcription regulatory region DNA binding
C2H2 zinc finger transcription factor
in utero embryonic development
positive regulation of neuroblast proliferation
brain development
positive regulation of cell proliferation
regulation of gene expression
cerebral cortex neuron differentiation
regulation of gene expression, epigenetic
positive regulation of transcription from RNA polymerase II promoter
neuron projection morphogenesis
brain morphogenesis
positive regulation of lymphocyte proliferation
regulation of neurogenesis
positive regulation of neurogenesis
transcription, DNA-templated
regulation of transcription, DNA-templated
multicellular organism development
regulation of histone H3-K4 methylation
histone H3-K4 trimethylation
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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