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Abnova
MLXIPL Monoclonal Antibody (5B2)
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Product Details
H00051085-M01
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2a, kappa
Class
Monoclonal
Type
Antibody
Clone
5B2
Immunogen
MLXIPL (NP_116569.1, 603 a.a. approximately 700 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Product may be used with Sandwich ELISA (Recombinant protein).
Immunogen sequence: PPAPSGSERR LSGDLSSMPG PGTLSVRVSP PQPILSRGRP DSNKTENRRI THISAEQKRR FNIKLGFDTL HGLVSTLSAQ PSLKVSKATT LQKTAEYI
Target Information
ChREBP is a transcription factor involved in activating genes that encode enzymes of fatty acid biosynthesis in liver and adipose. This protein may have relevance to lipid metabolism, obesity, and type II diabetes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: bHLH transcription factor; bHLHd14; bHLHZip transcription factor; carbohydrate response element binding protein; Carbohydrate-responsive element-binding protein; ChREBP; Class D basic helix-loop-helix protein 14; MLX interactor; MLX-interacting protein-like; Williams Beuren syndrome chromosome region 14; Williams-Beuren syndrome chromosomal region 14 protein; Williams-Beuren syndrome chromosome region 14 protein 1; Williams-Beuren syndrome chromosome region 14 protein 2; Williams-Beuren syndrome chromosome region 14 protein 3; WS basic-helix-loop-helix leucine zipper protein; WS-bHLH
Gene Aliases: BHLHD14; CHREBP; MIO; MLX; MLXIPL; MONDOB; WBSCR14; WS-bHLH
UniProt ID: (Human) Q9NP71
Entrez Gene ID: (Human) 51085
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
DNA binding
transcription factor activity, sequence-specific DNA binding
carbohydrate response element binding
protein homodimerization activity
protein heterodimerization activity
protein dimerization activity
RNA polymerase II sequence-specific DNA binding transcription factor binding
DNA-binding transcription factor binding
negative regulation of transcription from RNA polymerase II promoter
positive regulation of transcription from RNA polymerase II promoter by glucose
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
positive regulation of cell proliferation
lipid biosynthetic process
anatomical structure morphogenesis
glucose mediated signaling pathway
positive regulation of insulin secretion involved in cellular response to glucose stimulus
glucose homeostasis
positive regulation of fatty acid biosynthetic process
positive regulation of glycolytic process
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
positive regulation of lipid biosynthetic process
fatty acid homeostasis
triglyceride homeostasis
negative regulation of oxidative phosphorylation
energy homeostasis
negative regulation of signal transduction by p53 class mediator
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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