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Invitrogen
IL10RB Monoclonal Antibody (A8E11)
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FIGURE: 1 / 2
IL10RB Antibody (MA5-50604) in WB
Western blot analysis of IL10RB in different various lysates. Lane 1: Jurkat cell lysate; Lane 2: 293T cell lysate Lysates/proteins at 10 µg/Lane. Predicted band size: 37 kDa. Observed band size: 40 kDa. Exposure time: 2 minutes; 12% SDS-PAGE gel. Primary antibody IL10RB monoclonal antibody (Product # MA5-50604) with a dilution of 1:1,000 was used in 5% NFDM/TBST at room temperature for 2 hours. Goat Anti-Mouse IgG-HRP Secondary Antibody with a dilution of 1:100,000 was used for 1 hour at room temperature. Proteins were transferred to a PV... View More
Product Details
MA5-50604
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2a
Class
Monoclonal
Type
Antibody
Clone
A8E11
Immunogen
Synthetic peptide within Human IL-10RB aa 181-230/325.
Conjugate
Form
Liquid
Concentration
2 mg/mL
Amount
200 µg
Purification
Protein A
Storage buffer
PBS, pH 7.4, with 0.1% BSA, 40% glycerol
Contains
0.05% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Positive control: Jurkat cell lysate, 293T cell lysate, U87MG cell lysates.
Predicted band size: 37 kDa
Subcellular Location: Membrane.
Target Information
Natural killer (NK) cells in teleosts and their evolutionary homologue are a subpopulation of lymphocytes with properties that distinguish them from either B- or T-cells. NK cells are important effectors of innate immunity where they release cytokines, which in turn up-regulate other immunological functions. Monoclonal antibodies have been used to identify different surface antigens present on NK cells. These surface antigens have not only been used to identify NK cells, but also their functionally distinct subsets. The Cluster of Differentiation (CD) nomenclature was established to standardize the naming of NK cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CDw210b; CRF2-4; cytokine receptor class-II CRF2-4; Cytokine receptor class-II member 4; Cytokine receptor family 2 member 4; cytokine receptor family II, member 4; IL-10 receptor subunit beta; IL-10R subunit 2; IL-10R subunit beta; inte; interleukin 10 receptor, beta; Interleukin-10 receptor subunit 2; Interleukin-10 receptor subunit beta; unnamed protein product
Gene Aliases: CDW210B; CRF2-4; CRFB4; D21S58; D21S66; IBD25; IL-10R2; IL-10RB; IL10RB
UniProt ID: (Human) Q08334
Entrez Gene ID: (Human) 3588
inflammatory response
immune response
signal transduction
cytokine-mediated signaling pathway
type III interferon-mediated signaling pathway
positive regulation of JAK-STAT cascade
defense response to virus
cellular response to virus
interleukin-10-mediated signaling pathway
positive regulation of cellular respiration
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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