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Invitrogen
CHST8 Polyclonal Antibody
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Product Details
PA5-101487
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human CHST8(Accession Q9H2A9), corresponding to amino acid residues V345-L395.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of total CHST8.
Target Information
The protein encoded by this gene belongs to the sulfotransferase 2 family. It is predominantly expressed in the pituitary gland, and is localized to the Golgi membrane. This protein catalyzes the transfer of sulfate to position 4 of non-reducing N-acetylgalactosamine (GalNAc) residues in both N-glycans and O-glycans. It is responsible for sulfation of GalNAc on luteinizing hormone (LH), which is required for production of the sex hormones. Mice lacking this enzyme, exhibit increased levels of circulating LH, and precocious sexual maturation of both male and female mice. Alternatively spliced transcript variants have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8; carbohydrate sulfotransferase; Carbohydrate sulfotransferase 8; GalNAc-4-O-sulfotransferase 1; GALNAC-4-ST1; GalNAc4ST-1; N-acetylgalactosamine-4-O-sulfotransferase 1
Gene Aliases: 1500011J21Rik; AI426009; CHST8; GalNAc4ST; GALNAC4ST1; PSS3
UniProt ID: (Human) Q9H2A9, (Mouse) Q8BQ86
Entrez Gene ID: (Human) 64377, (Rat) 308511, (Mouse) 68947
N-acetylgalactosamine 4-O-sulfotransferase activity
protein binding
sulfotransferase activity
transferase activity
N-acetylglucosamine 6-O-sulfotransferase activity
heparan sulfate 2-O-sulfotransferase activity
HNK-1 sulfotransferase activity
heparan sulfate 6-O-sulfotransferase activity
trans-9R,10R-dihydrodiolphenanthrene sulfotransferase activity
1-phenanthrol sulfotransferase activity
3-phenanthrol sulfotransferase activity
4-phenanthrol sulfotransferase activity
trans-3,4-dihydrodiolphenanthrene sulfotransferase activity
9-phenanthrol sulfotransferase activity
2-phenanthrol sulfotransferase activity
phenanthrol sulfotransferase activity
1-hydroxypyrene sulfotransferase activity
galactose 3-O-sulfotransferase activity
proteoglycan sulfotransferase activity
cholesterol sulfotransferase activity
hydroxyjasmonate sulfotransferase activity
transferase
metabolite interconversion enzyme
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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