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Invitrogen
SLC9A6 Polyclonal Antibody
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Product Details
PA5-36997
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide corresponding to amino acids 602-647 of human SLC9A6
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
This antibody detects endogenous protein at a molecular weight of 74 kDa.
Purity is >95% by SDS-PAGE.
Target Information
Na+/H+ exchangers-1-6 (Na+/H+ antiporters, NHE-1-6) are integral membrane proteins that are expressed in most mammalian tissues where they regulate intracellular pH and cell volume. NHEs mediate the secondary active extrusion of hydrogen (H+) ions out of cells in exchange for extracellular sodium (Na+). Excluding NHE-1, which is ubiquitously expressed, the NHE isoforms 2-6 have distinct tissue- and cell type-dependent expression, and inhibitiory characteristics by amiloride analogs.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: KIAA0267; Na(+)/H(+) exchanger 6; NHE-6; Sodium/hydrogen exchanger; Sodium/hydrogen exchanger 6; solute carrier family 9 (sodium/hydrogen exchanger), isoform 6; solute carrier family 9 (sodium/hydrogen exchanger), member 6; Solute carrier family 9 member 6; solute carrier family 9, subfamily A (NHE6, cation proton antiporter 6), member 6; unnamed protein product
Gene Aliases: 3732426M05; 6430520C02Rik; KIAA0267; mKIAA0267; MRSA; MRXSCH; NDPACX; NHE6; RGD1563582; SLC9A6
UniProt ID: (Human) Q92581, (Mouse) A1L3P4
Entrez Gene ID: (Human) 10479, (Rat) 302863, (Mouse) 236794
ion transport
cation transport
sodium ion transport
regulation of pH
establishment of cell polarity
axon extension
neuron projection morphogenesis
regulation of intracellular pH
transmembrane transport
potassium ion transmembrane transport
dendrite extension
sodium ion import across plasma membrane
hydrogen ion transmembrane transport
biological_process
proton transport
brain-derived neurotrophic factor receptor signaling pathway
sodium ion transmembrane transport
synapse organization
regulation of neurotrophin TRK receptor signaling pathway
dendritic spine development
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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