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          • Home
          • › Search Tool
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          • › Hs06937891_cn
          See other IGF1 CNV Assays ›
          Gene Symbol
          IGF1
          Assay Reference Genome
          Location

          Chr.12:102481575 on build GRCh38
          Cytoband
          12q23.2
          Assay ID Hs06937891_cn
          Size
          Availability Made To Order
          Catalog # 4400291
          Price
          Your Price
          Online offer:
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          • Genomic Map
          • Assay Details
          • More Information

          Genomic Map

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          Assay Details

          Target Gene Details

          Entrez Gene ID:

          3479

          Gene Name:

          insulin like growth factor 1

          Gene Aliases:

          IGF-I, IGFI, MGF

          Location:

          Chr.12:102395867-102481839 on Build GRCh38

          Assay Gene Location:

          Within Intron 1
          Gene Symbol Transcript Accession Exon Location Assay Transcript Location Protein ID
          IGF1 XM_017019259.1 XP_016874748.1
          XM_017019262.1 XP_016874751.1
          XM_017019263.1 XP_016874752.1

          Target Copy Number Variation Details

          DGV Version:

          Release date: 2016-05-15, GRCh GRCh38
          Target
          Variation
          Location CNV
          Subtype
          Genes
          nsv832498 Chr.12:102334798 - 102519791 on Build GRCh38 Gain IGF1
          nsv832499 Chr.12:102414522 - 102581480 on Build GRCh38 Gain IGF1

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          More Information


          Set Membership:

          Intragenic Intronic Non-exonic DGV Variation

          Panther Classification:

          Molecular Function -

          growth factor

          Gene Ontology Categories:

          Function(s) Process(es)

          activation of MAPK activity
          skeletal system development
          response to hypoxia
          cell activation
          platelet degranulation
          DNA replication
          regulation of translation
          movement of cell or subcellular component
          signal transduction
          Ras protein signal transduction
          muscle organ development
          female pregnancy
          aging
          response to nutrient
          memory
          cell proliferation
          positive regulation of cell proliferation
          response to heat
          glycolate metabolic process
          regulation of gene expression
          positive regulation of glycoprotein biosynthetic process
          positive regulation of cardiac muscle hypertrophy
          phosphatidylinositol 3-kinase signaling
          positive regulation of phosphatidylinositol 3-kinase signaling
          response to activity
          skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration
          muscle hypertrophy
          myotube cell development
          positive regulation of smooth muscle cell migration
          proteoglycan biosynthetic process
          positive regulation of cell migration
          response to caffeine
          activation of protein kinase B activity
          response to lipopolysaccharide
          cellular response to insulin stimulus
          positive regulation of protein import into nucleus, translocation
          negative regulation of smooth muscle cell apoptotic process
          response to nicotine
          bone mineralization involved in bone maturation
          regulation of multicellular organism growth
          positive regulation of activated T cell proliferation
          positive regulation of tyrosine phosphorylation of Stat5 protein
          negative regulation of apoptotic process
          positive regulation of DNA binding
          positive regulation of MAPK cascade
          protein kinase B signaling
          positive regulation of insulin-like growth factor receptor signaling pathway
          cellular protein metabolic process
          myoblast differentiation
          positive regulation of fat cell differentiation
          positive regulation of osteoblast differentiation
          positive regulation of glycogen biosynthetic process
          positive regulation of DNA replication
          positive regulation of glycolytic process
          positive regulation of mitotic nuclear division
          positive regulation of transcription, DNA-templated
          positive regulation of transcription from RNA polymerase II promoter
          positive regulation of glucose import
          positive regulation of Ras protein signal transduction
          insulin-like growth factor receptor signaling pathway
          phosphatidylinositol-mediated signaling
          positive regulation of fibroblast proliferation
          positive regulation of smooth muscle cell proliferation
          positive regulation of epithelial cell proliferation
          positive regulation of protein secretion
          positive regulation of peptidyl-tyrosine phosphorylation
          protein stabilization
          detection of mechanical stimulus involved in sensory perception
          response to glucocorticoid
          myoblast proliferation
          regulation of calcium ion transport
          negative regulation of oocyte development
          positive regulation of cell growth involved in cardiac muscle cell development
          ERK1 and ERK2 cascade
          positive regulation of calcineurin-NFAT signaling cascade
          cellular response to electrical stimulus
          cellular response to estradiol stimulus
          negative regulation of release of cytochrome c from mitochondria
          negative regulation of neuron death
          positive regulation of trophectodermal cell proliferation
          negative regulation of cholangiocyte apoptotic process
          positive regulation of transcription regulatory region DNA binding
          negative regulation of extrinsic apoptotic signaling pathway
          insulin receptor binding
          insulin-like growth factor receptor binding
          integrin binding
          hormone activity
          steroid binding
          protein binding
          growth factor activity

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