Assay Details

Gene Symbol: MMP1
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_001145938.1	NP_001139410.1	6 - 7	892		133
RefSeq	NM_002421.3	NP_002412.1	6 - 7	1044		133
GenBank mRNA	AK024818.1	-	6 - 7	967		133
	AK098450.1	-	7 - 8	899		133
	AK130687.1	-	6 - 7	967		133
	AK223034.1	-	5 - 6	670		133
	AK223035.1	-	6 - 7	925		133
	AK223036.1	-	4 - 5	508		133
	AK223056.1	-	5 - 6	710		133
	AK223281.1	-	6 - 7	967		133
	AK225495.1	-	5 - 6	735		133
	AK297723.1	-	6 - 7	815		133
	AK301340.1	-	6 - 7	757		133
	BC013118.1	-	2 - 3	192		133
	BC013875.2	-	6 - 7	943	3834572	133
	BT006874.1	-	6 - 7	901		133
	BT020147.1	-	6 - 7	901		133
	M13509.1	-	6 - 7	969		133
	X05231.1	-	6 - 7	967		133
	X54925.1	-	6 - 7	969		133

More Information

Updated Mapping Information

This assay targets the same location as Clariom D transcript cluster(s) TC1100012131.hg.1
This assay targets the same location as HTA transcript cluster(s) TC11002234.hg.1

Set Membership:

Ambion siRNA available

Amplicon length greater than or equal to 101

Protease

Immune Tolerance Network

Mammalian Gene Collection

Homo sapiens

Human Tumor Metastasis Panel

Inventoried

MicroArray Quality Control (MAQC)

Human Tumor Metastasis

Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene MMP1

Panther Classification:

Molecular Function -

metalloprotease

Gene Ontology Categories:

Function(s) Process(es)

MicroArray Probes:

Affymetrix

Array Name	Probe IDs	Targets	Target Type
Affymetrix Human Transcriptome Array 2.0	TC1100012131.hg.1	ENST00000315274.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC1100012131.hg.1	ENST00000315274.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC1100012131.hg.1	ENST00000315274.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC1100012131.hg.1	ENST00000315274.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC1100012131.hg.1	ENST00000315274.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC1100012131.hg.1	ENST00000315274.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC1100012131.hg.1	ENST00000315274.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC1100012131.hg.1	ENST00000315274.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC1100012131.hg.1	ENST00000315274.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC1100012131.hg.1	ENST00000315274.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC1100012131.hg.1	ENST00000315274.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC1100012131.hg.1	ENST00000315274.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC1100012131.hg.1	ENST00000315274.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC1100012131.hg.1	ENST00000315274.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC1100012131.hg.1	ENST00000315274.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC1100012131.hg.1	ENST00000315274.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC1100012131.hg.1	NM_001145938.1	Refseq
Affymetrix Human Transcriptome Array 2.0	TC1100012131.hg.1	NM_001145938.1	Refseq
Affymetrix Human Transcriptome Array 2.0	TC1100012131.hg.1	NM_001145938.1	Refseq
Affymetrix Human Transcriptome Array 2.0	TC1100012131.hg.1	NM_001145938.1	Refseq
Affymetrix Human Transcriptome Array 2.0	TC1100012131.hg.1	NM_001145938.1	Refseq
Affymetrix Human Transcriptome Array 2.0	TC1100012131.hg.1	NM_001145938.1	Refseq
Affymetrix Human Transcriptome Array 2.0	TC1100012131.hg.1	NM_001145938.1	Refseq
Affymetrix Human Transcriptome Array 2.0	TC1100012131.hg.1	NM_001145938.1	Refseq
Affymetrix Human Transcriptome Array 2.0	TC1100012131.hg.1	NM_001145938.1	Refseq
Affymetrix Human Transcriptome Array 2.0	TC1100012131.hg.1	NM_001145938.1	Refseq
Affymetrix Human Transcriptome Array 2.0	TC1100012131.hg.1	NM_001145938.1	Refseq
Affymetrix Human Transcriptome Array 2.0	TC1100012131.hg.1	NM_001145938.1	Refseq
Affymetrix Human Transcriptome Array 2.0	TC1100012131.hg.1	NM_001145938.1	Refseq
Affymetrix Human Transcriptome Array 2.0	TC1100012131.hg.1	NM_001145938.1	Refseq
Affymetrix Human Transcriptome Array 2.0	TC1100012131.hg.1	NM_001145938.1	Refseq
Affymetrix Human Transcriptome Array 2.0	TC1100012131.hg.1	NM_002421.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC1100012131.hg.1	NM_002421.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC1100012131.hg.1	NM_002421.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC1100012131.hg.1	NM_002421.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC1100012131.hg.1	NM_002421.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC1100012131.hg.1	NM_002421.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC1100012131.hg.1	NM_002421.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC1100012131.hg.1	NM_002421.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC1100012131.hg.1	NM_002421.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC1100012131.hg.1	NM_002421.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC1100012131.hg.1	NM_002421.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC1100012131.hg.1	NM_002421.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC1100012131.hg.1	NM_002421.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC1100012131.hg.1	NM_002421.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC1100012131.hg.1	NM_002421.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC1100012131.hg.1	NM_002421.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC1100012131.hg.1	NM_002421.3	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR11026690.hg.1	ENST00000315274.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR11026690.hg.1	NM_001145938.1	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR11026690.hg.1	NM_002421.3	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR11026690.hg.1	TC11002234.hg.1	HTA TC
Affymetrix Human Transcriptome Array 2.0	PSR11026691.hg.1	ENST00000315274.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR11026691.hg.1	NM_001145938.1	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR11026691.hg.1	NM_002421.3	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR11026691.hg.1	TC11002234.hg.1	HTA TC
Affymetrix Human Clariom D Assay	PSR1100193247.hg.1	ENST00000315274.6	Ensembl
Affymetrix Human Clariom D Assay	PSR1100193247.hg.1	NM_001145938.1	Refseq
Affymetrix Human Clariom D Assay	PSR1100193247.hg.1	NM_002421.3	Refseq
Affymetrix Human Clariom D Assay	PSR1100193247.hg.1	ENST00000315274.6	Ensembl
Affymetrix Human Clariom D Assay	PSR1100193247.hg.1	NM_001145938.1	Refseq
Affymetrix Human Clariom D Assay	PSR1100193247.hg.1	NM_002421.3	Refseq
Affymetrix Human Clariom D Assay	PSR1100193247.hg.1	TC1100012131.hg.1	Clariom D TC
Affymetrix Human Clariom D Assay	PSR1100193248.hg.1	ENST00000315274.6	Ensembl
Affymetrix Human Clariom D Assay	PSR1100193248.hg.1	NM_001145938.1	Refseq
Affymetrix Human Clariom D Assay	PSR1100193248.hg.1	NM_002421.3	Refseq
Affymetrix Human Clariom D Assay	PSR1100193248.hg.1	ENST00000315274.6	Ensembl
Affymetrix Human Clariom D Assay	PSR1100193248.hg.1	NM_001145938.1	Refseq
Affymetrix Human Clariom D Assay	PSR1100193248.hg.1	NM_002421.3	Refseq
Affymetrix Human Clariom D Assay	PSR1100193248.hg.1	TC1100012131.hg.1	Clariom D TC
Affymetrix Human Clariom D Assay	TC1100012131.hg.1	ENST00000315274.6	Ensembl
Affymetrix Human Clariom D Assay	TC1100012131.hg.1	ENST00000315274.6	Ensembl
Affymetrix Human Clariom D Assay	TC1100012131.hg.1	ENST00000315274.6	Ensembl
Affymetrix Human Clariom D Assay	TC1100012131.hg.1	ENST00000315274.6	Ensembl
Affymetrix Human Clariom D Assay	TC1100012131.hg.1	ENST00000315274.6	Ensembl
Affymetrix Human Clariom D Assay	TC1100012131.hg.1	ENST00000315274.6	Ensembl
Affymetrix Human Clariom D Assay	TC1100012131.hg.1	ENST00000315274.6	Ensembl
Affymetrix Human Clariom D Assay	TC1100012131.hg.1	ENST00000315274.6	Ensembl
Affymetrix Human Clariom D Assay	TC1100012131.hg.1	ENST00000315274.6	Ensembl
Affymetrix Human Clariom D Assay	TC1100012131.hg.1	ENST00000315274.6	Ensembl
Affymetrix Human Clariom D Assay	TC1100012131.hg.1	ENST00000315274.6	Ensembl
Affymetrix Human Clariom D Assay	TC1100012131.hg.1	ENST00000315274.6	Ensembl
Affymetrix Human Clariom D Assay	TC1100012131.hg.1	ENST00000315274.6	Ensembl
Affymetrix Human Clariom D Assay	TC1100012131.hg.1	ENST00000315274.6	Ensembl
Affymetrix Human Clariom D Assay	TC1100012131.hg.1	ENST00000315274.6	Ensembl
Affymetrix Human Clariom D Assay	TC1100012131.hg.1	ENST00000315274.6	Ensembl
Affymetrix Human Clariom D Assay	TC1100012131.hg.1	NM_001145938.1	Refseq
Affymetrix Human Clariom D Assay	TC1100012131.hg.1	NM_001145938.1	Refseq
Affymetrix Human Clariom D Assay	TC1100012131.hg.1	NM_001145938.1	Refseq
Affymetrix Human Clariom D Assay	TC1100012131.hg.1	NM_001145938.1	Refseq
Affymetrix Human Clariom D Assay	TC1100012131.hg.1	NM_001145938.1	Refseq
Affymetrix Human Clariom D Assay	TC1100012131.hg.1	NM_001145938.1	Refseq
Affymetrix Human Clariom D Assay	TC1100012131.hg.1	NM_001145938.1	Refseq
Affymetrix Human Clariom D Assay	TC1100012131.hg.1	NM_001145938.1	Refseq
Affymetrix Human Clariom D Assay	TC1100012131.hg.1	NM_001145938.1	Refseq
Affymetrix Human Clariom D Assay	TC1100012131.hg.1	NM_001145938.1	Refseq
Affymetrix Human Clariom D Assay	TC1100012131.hg.1	NM_001145938.1	Refseq
Affymetrix Human Clariom D Assay	TC1100012131.hg.1	NM_001145938.1	Refseq
Affymetrix Human Clariom D Assay	TC1100012131.hg.1	NM_001145938.1	Refseq
Affymetrix Human Clariom D Assay	TC1100012131.hg.1	NM_001145938.1	Refseq
Affymetrix Human Clariom D Assay	TC1100012131.hg.1	NM_001145938.1	Refseq
Affymetrix Human Clariom D Assay	TC1100012131.hg.1	NM_002421.3	Refseq
Affymetrix Human Clariom D Assay	TC1100012131.hg.1	NM_002421.3	Refseq
Affymetrix Human Clariom D Assay	TC1100012131.hg.1	NM_002421.3	Refseq
Affymetrix Human Clariom D Assay	TC1100012131.hg.1	NM_002421.3	Refseq
Affymetrix Human Clariom D Assay	TC1100012131.hg.1	NM_002421.3	Refseq
Affymetrix Human Clariom D Assay	TC1100012131.hg.1	NM_002421.3	Refseq
Affymetrix Human Clariom D Assay	TC1100012131.hg.1	NM_002421.3	Refseq
Affymetrix Human Clariom D Assay	TC1100012131.hg.1	NM_002421.3	Refseq
Affymetrix Human Clariom D Assay	TC1100012131.hg.1	NM_002421.3	Refseq
Affymetrix Human Clariom D Assay	TC1100012131.hg.1	NM_002421.3	Refseq
Affymetrix Human Clariom D Assay	TC1100012131.hg.1	NM_002421.3	Refseq
Affymetrix Human Clariom D Assay	TC1100012131.hg.1	NM_002421.3	Refseq
Affymetrix Human Clariom D Assay	TC1100012131.hg.1	NM_002421.3	Refseq
Affymetrix Human Clariom D Assay	TC1100012131.hg.1	NM_002421.3	Refseq
Affymetrix Human Clariom D Assay	TC1100012131.hg.1	NM_002421.3	Refseq
Affymetrix Human Clariom D Assay	TC1100012131.hg.1	NM_002421.3	Refseq
Affymetrix Human Clariom D Assay	TC1100012131.hg.1	NM_002421.3	Refseq

Citations (23)

Up-regulation of alveolar macrophage matrix metalloproteinases in HIV1(+) smokers with early emphysema.

Authors: Kaner RJ, Santiago F, Crystal RG
Journal: J Leukoc Biol - Page No 913 (Thu Oct 01 00:00:00 UTC 2009)
Volume (Year): 86 (2009)
Product Usage: -

Role of hypoxia-inducible factor-1alpha in hypoxia-induced expressions of IL-8, MMP-1 and MMP-3 in rheumatoid fibroblast-like synoviocytes.

Authors: Ahn JK, Koh EM, Cha HS, Lee YS, Kim J, Bae EK, Ahn KS
Journal: Rheumatology (Oxford) - Page No 834 (Sun Jun 01 00:00:00 UTC 2008)
Volume (Year): 47 (2008)
Product Usage: -

Effects of 10 cigarette smoke condensates on primary human airway epithelial cells by comparative gene and cytokine expression studies.

Authors: Pickett G, Seagrave J, Boggs S, Polzin G, Richter P, Tesfaigzi Y
Journal: Toxicol Sci - Page No 79 (Mon Mar 01 00:00:00 UTC 2010)
Volume (Year): 114 (2010)
Product Usage: -

Mechanisms of the inhibitory effect of epigallocatechin-3-gallate on cultured human vascular smooth muscle cell invasion.

Authors: Cheng XW, Kuzuya M, Nakamura K, Liu Z, Di Q, Hasegawa J, Iwata M, Murohara T, Yokota M, Iguchi A
Journal: Arterioscler Thromb Vasc Biol - Page No 1864 (Thu Sep 01 00:00:00 UTC 2005)
Volume (Year): 25 (2005)
Product Usage: -

Identification of molecular distinctions between normal breast-associated fibroblasts and breast cancer-associated fibroblasts.

Authors: Sadlonova A, Bowe DB, Novak Z, Mukherjee S, Duncan VE, Page GP, Frost AR
Journal: Cancer Microenviron - Page No 9 (Tue Dec 01 00:00:00 UTC 2009)
Volume (Year): 2 (2009)
Product Usage: -

Matrix and TGF-beta-related gene expression during human dental pulp stem cell (DPSC) mineralization.

Authors: Liu J, Jin T, Chang S, Ritchie HH, Smith AJ, Clarkson BH
Journal: In Vitro Cell Dev Biol Anim - Page No 120 (Thu Mar 01 00:00:00 UTC 2007)
Volume (Year): 43 (2007)
Product Usage: -

Phagocytosis and remodeling of collagen matrices.

Authors: Abraham LC, Dice JF, Lee K, Kaplan DL
Journal: Exp Cell Res - Page No 1045 (Sat Mar 10 00:00:00 UTC 2007)
Volume (Year): 313 (2007)
Product Usage: -

The expression of proinflammatory cytokines and matrix metalloproteinases in the synovial membranes of patients with osteoarthritis compared with traumatic knee disorders.

Authors: Wassilew GI, Lehnigk U, Duda GN, Taylor WR, Matziolis G, Dynybil C
Journal: Arthroscopy - Page No 1096 (Sun Aug 01 00:00:00 UTC 2010)
Volume (Year): 26 (2010)
Product Usage: -

Relation between intracavernosal dose of prostaglandin Pge 1 and mean duration of erection in men with different underlying causes of erectile dysfunction.

Authors: Bratus D, Hlebic G, Hajdinjak T
Journal: Croat Med J - Page No 76 (Thu Feb 01 00:00:00 UTC 2007)
Volume (Year): 48 (2007)
Product Usage: -

UV-induced DNA damage initiates release of MMP-1 in human skin.

Authors: Dong KK, Damaghi N, Picart SD, Markova NG, Obayashi K, Okano Y, Masaki H, Grether-Beck S, Krutmann J, Smiles KA, Yarosh DB
Journal: Exp Dermatol - Page No 1037 (Mon Dec 01 00:00:00 UTC 2008)
Volume (Year): 17 (2008)
Product Usage: -

Protein isoprenylation regulates secretion of matrix metalloproteinase 1 from rheumatoid synovial fibroblasts: effects of statins and farnesyl and geranylgeranyl transferase inhibitors.

Authors: Abeles AM, Marjanovic N, Park J, Attur M, Chan ES, Al-Mussawir HE, Dave M, Fisher MC, Stuchin SA, Abramson SB, Pillinger MH
Journal: Arthritis Rheum - Page No 2840 (Sat Sep 01 00:00:00 UTC 2007)
Volume (Year): 56 (2007)
Product Usage: -

Impact of collagen structure on matrix trafficking by human fibroblasts.

Authors: Abraham LC, Vorrasi J, Kaplan DL
Journal: J Biomed Mater Res A - Page No 39 (Thu Jul 01 00:00:00 UTC 2004)
Volume (Year): 70 (2004)
Product Usage: -

Liver X receptor is a therapeutic target for photoaging and chronological skin aging.

Authors: Chang KC, Shen Q, Oh IG, Jelinsky SA, Jenkins SF, Wang W, Wang Y, LaCava M, Yudt MR, Thompson CC, Freedman LP, Chung JH, Nagpal S
Journal: Mol Endocrinol - Page No 2407 (Sat Nov 01 00:00:00 UTC 2008)
Volume (Year): 22 (2008)
Product Usage: -

Anabolic and catabolic responses of human articular chondrocytes to varying oxygen percentages.

Authors: Strobel S, Loparic M, Wendt D, Schenk AD, Candrian C, Lindberg RL, Moldovan F, Barbero A, Martin I
Journal: Arthritis Res Ther - Page No R34 (Fri Jan 01 00:00:00 UTC 2010)
Volume (Year): 12 (2010)
Product Usage: -

Altered production of extra-cellular matrix components by muscle-derived Duchenne muscular dystrophy fibroblasts before and after TGF-beta1 treatment.

Authors: Zanotti S, Gibertini S, Mora M
Journal: Cell Tissue Res - Page No 397 (Mon Feb 01 00:00:00 UTC 2010)
Volume (Year): 339 (2010)
Product Usage: -

First look at the effect of overexpression of TIGR/MYOC on the transcriptome of the human trabecular meshwork.

Authors: Borras T, Bryant PA, Chisolm SS
Journal: Exp Eye Res - Page No 1002 (Thu Jun 01 00:00:00 UTC 2006)
Volume (Year): 82 (2006)
Product Usage: -

Nitric oxide donors selectively reduce the expression of matrix metalloproteinases-8 and -9 by human diabetic skin fibroblasts.

Authors: Burrow JW, Koch JA, Chuang HH, Zhong W, Dean DD, Sylvia VL
Journal: J Surg Res - Page No 90 (Fri Jun 01 00:00:00 UTC 2007)
Volume (Year): 140 (2007)
Product Usage: -

Cervical tissue engineering using silk scaffolds and human cervical cells.

Authors: House M, Sanchez CC, Rice WL, Socrate S, Kaplan DL
Journal: Tissue Eng Part A - Page No 2101 (Tue Jun 01 00:00:00 UTC 2010)
Volume (Year): 16 (2010)
Product Usage: -

Induction of matrix metalloproteinase-1 by small interfering RNA targeting connective tissue growth factor in dermal fibroblasts from patients with systemic sclerosis.

Authors: Ishibuchi H, Abe M, Yokoyama Y, Ishikawa O
Journal: Exp Dermatol - Page No e111 (Sun Aug 01 00:00:00 UTC 2010)
Volume (Year): 19 (2010)
Product Usage: -

Signal transducer and activator of transcription 3 activation promotes invasive growth of colon carcinomas through matrix metalloproteinase induction.

Authors: Tsareva SA, Moriggl R, Corvinus FM, Wiederanders B, Schutz A, Kovacic B, Friedrich K
Journal: Neoplasia - Page No 279 (Sun Apr 01 00:00:00 UTC 2007)
Volume (Year): 9 (2007)
Product Usage: -

Multiplex preamplification of specific cDNA targets prior to gene expression analysis by TaqMan Arrays.

Authors: Mengual L, Burset M, Marin-Aguilera M, Ribal MJ, Alcaraz A
Journal: Bmc Res Notes - Page No 21 (Tue Jan 01 00:00:00 UTC 2008)
Volume (Year): 1 (2008)
Product Usage: -

Role for cathepsin K in emphysema in smoke-exposed guinea pigs.

Authors: Golovatch P, Mercer BA, Lemaitre V, Wallace A, Foronjy RF, D'Armiento J
Journal: Exp Lung Res - Page No 631 (Thu Oct 01 00:00:00 UTC 2009)
Volume (Year): 35 (2009)
Product Usage: -

Adult human bone marrow stromal cells regulate expression of their MMPs and TIMPs in differentiation type-specific manner.

Authors: Mauney J, Volloch V
Journal: Matrix Biol - Page No 3 (Fri Jan 01 00:00:00 UTC 2010)
Volume (Year): 29 (2010)
Product Usage: -

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Genomic Map