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          • Home
          • › Search Tool
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          • › Hs06630780_s1
          See other CASP8 GE Assays ›
          Gene Symbol:
          CASP8
          Gene Name:
          caspase 8
          Gene Aliases:
          ALPS2B, CAP4, Casp-8, FLICE, MACH, MCH5
          Chromosome Location:
          Chr.2: 201233443 - 201287711 on Build GRCh38
          Species:
          Human
          Species Specific ID (Flybase ID):
          -
          Assay ID Hs06630780_s1
          Best Coverage
          Size
          Availability Inventoried
          Catalog # 4331182
          Price
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          • Genomic Map
          • Assay Details
          • More Information

          Genomic Map

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          Assay Details

          Gene Symbol: CASP8
          Interrogated Sequence Translated Protein Exon Boundary Assay Location IMAGE Clone ID Amplicon Length
          RefSeq NM_001080124.1 NP_001073593.1 7 946 90
          NM_001080125.1 NP_001073594.1 7 1134 90
          NM_001228.4 NP_001219.2 8 1110 90
          NM_033355.3 NP_203519.1 8 965 90
          NM_033356.3 NP_203520.1 6 851 90
          NM_033358.3 NP_203522.1 7 994 90
          NR_111983.1 7 1134 90
          XM_005246885.1 XP_005246942.1 6 909 90
          XM_005246886.1 XP_005246943.1 7 880 90
          XM_005246887.1 XP_005246944.1 8 1032 90
          XM_005246888.1 XP_005246945.1 8 974 90
          XM_005246889.1 XP_005246946.1 7 851 90
          XM_005246890.3 XP_005246947.1 7 858 90
          XM_005246891.4 XP_005246948.1 7 1098 90
          XM_005246892.1 XP_005246949.1 6 806 90
          XM_005246893.2 XP_005246950.1 6 889 90
          XM_005246894.3 XP_005246951.1 7 964 90
          XM_005246895.2 XP_005246952.1 5 844 90
          XM_006712789.1 XP_006712852.1 8 991 90
          XM_006712790.3 XP_006712853.1 7 870 90
          XM_006712793.2 XP_006712856.1 7 967 90
          XM_011511969.1 XP_011510271.1 5 435 90
          GenBank mRNA AB451282.1 - 5 711 90
          AB451414.1 - 5 711 90
          AF009620.1 - 5 711 90
          AF380342.1 - 7 841 90
          AF422927.1 - 7 934 90
          AF422928.1 - 8 953 90
          BC028223.2 - 6 783 90
          BC068050.1 - 6 801 6421760 90
          BX395849.2 - 6 800 90
          U58143.1 - 6 756 90
          U60520.1 - 8 1063 90
          X98172.1 - 7 1047 90
          X98173.1 - 6 783 90
          X98175.1 - 3 261 90
          X98176.1 - 7 880 90
          X98177.1 - 6 756 90
          X98178.1 - 5 711 90

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          More Information


          Set Membership:

          Ambion siRNA available Amplicon length between 86 and 100 3' Most Mammalian Gene Collection Detect Genomic DNA Recommended Assay Homo sapiens Inventoried Both primers and probe map within a single exon

          Matching Ambion siRNAs:

          Click here to find siRNAs for Gene CASP8

          Panther Classification:

          Molecular Function -

          protease

          Gene Ontology Categories:

          Function(s) Process(es)

          proteolysis
          apoptotic process
          activation of cysteine-type endopeptidase activity involved in apoptotic process
          cellular component disassembly involved in execution phase of apoptosis
          cell surface receptor signaling pathway
          response to cold
          regulation of tumor necrosis factor-mediated signaling pathway
          regulation of necrotic cell death
          natural killer cell activation
          macrophage differentiation
          response to cobalt ion
          response to estradiol
          response to lipopolysaccharide
          response to tumor necrosis factor
          TRIF-dependent toll-like receptor signaling pathway
          TRAIL-activated apoptotic signaling pathway
          suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process
          T cell activation
          B cell activation
          positive regulation of I-kappaB kinase/NF-kappaB signaling
          negative regulation of I-kappaB kinase/NF-kappaB signaling
          response to ethanol
          positive regulation of macrophage differentiation
          positive regulation of proteolysis
          response to antibiotic
          protein heterooligomerization
          proteolysis involved in cellular protein catabolic process
          syncytiotrophoblast cell differentiation involved in labyrinthine layer development
          nucleotide-binding oligomerization domain containing signaling pathway
          cellular response to mechanical stimulus
          cellular response to organic cyclic compound
          death-inducing signaling complex assembly
          apoptotic signaling pathway
          extrinsic apoptotic signaling pathway
          execution phase of apoptosis
          activation of cysteine-type endopeptidase activity
          activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway
          positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway
          regulation of extrinsic apoptotic signaling pathway via death domain receptors
          negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
          cysteine-type endopeptidase activity
          death receptor binding
          tumor necrosis factor receptor binding
          protein binding
          peptidase activity
          cysteine-type peptidase activity
          ubiquitin protein ligase binding
          protein complex binding
          death effector domain binding
          identical protein binding
          scaffold protein binding
          cysteine-type endopeptidase activity involved in apoptotic process
          cysteine-type endopeptidase activity involved in apoptotic signaling pathway

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