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          System Message

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          LOADING ...
          See other EIF2AK2 SIRNA Assays ›
          Gene Symbol:
          EIF2AK2
          Gene Name:
          eukaryotic translation initiation factor 2 alpha kinase 2
          Gene Aliases:
          EIF2AK1, PKR, PPP1R83, PRKR
          Chromosome Location:
          Chr.2: 37099210 - 37157065 on Build GRCh38
          UniGene ID:
          Hs.131431
          Species:
          Human
          Species Specific ID (Flybase ID):
          -
          siRNA ID 103681

          Purification
          Size
          Availability Inventoried
          Catalog # AM16708
          Price
          Your Price
          Online offer:
          Check your price ›
          • Genomic Map
          • siRNA Details
          • More Information

          Genomic Map

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          siRNA Details

          Gene Symbol: EIF2AK2
          Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
          RefSeq NM_001135651.2 NP_001129123.1 4, 5 571
          NM_001135652.2 NP_001129124.1 2, 3 264
          NM_002759.3 NP_002750.1 4, 5 805
          XM_011532987.2 XP_011531289.1 4, 5 505
          XM_017004503.1 XP_016859992.1 4, 5 501
          GenBank mRNA AK290655.1 - 4, 5 491
          AK313818.1 - 3, 4 328
          AY302136.1 - 2, 3 248
          BC007769.2 - 3, 4 347
          BC022314.1 - 4, 5 459
          BC040851.1 - 4, 5 571
          BC057805.1 - 4, 5 476
          BC093676.1 - 2, 3 276 7939521
          BC101475.1 - 2, 3 276 8068981
          BC143228.1 - 2, 3 275
          BC143230.1 - 2, 3 276 9051731
          M35663.1 - 3, 4 434
          M85294.1 - 2, 3 278

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          More Information


          Panther Classification:

          Molecular Function -

          non-receptor serine/threonine protein kinase

          Gene Ontology Categories:

          Function(s) Process(es)

          activation of MAPKK activity
          positive regulation of cytokine production
          transcription, DNA-templated
          translation
          protein phosphorylation
          negative regulation of cell proliferation
          response to mechanical stimulus
          response to virus
          response to toxic substance
          regulation of translational initiation by eIF2 alpha phosphorylation
          negative regulation of translation
          peptidyl-tyrosine phosphorylation
          evasion or tolerance by virus of host immune response
          endoplasmic reticulum unfolded protein response
          response to lipopolysaccharide
          positive regulation of chemokine production
          positive regulation of stress-activated MAPK cascade
          response to vitamin E
          negative regulation of osteoblast proliferation
          regulation of protein phosphatase type 2A activity
          cellular response to amino acid starvation
          response to interferon-alpha
          positive regulation of apoptotic process
          negative regulation of apoptotic process
          response to exogenous dsRNA
          negative regulation of viral genome replication
          innate immune response
          protein autophosphorylation
          positive regulation of NF-kappaB transcription factor activity
          defense response to virus
          regulation of NLRP3 inflammasome complex assembly
          positive regulation of NIK/NF-kappaB signaling
          regulation of hematopoietic progenitor cell differentiation
          regulation of hematopoietic stem cell proliferation
          regulation of hematopoietic stem cell differentiation
          double-stranded RNA binding
          protein kinase activity
          protein serine/threonine kinase activity
          eukaryotic translation initiation factor 2alpha kinase activity
          non-membrane spanning protein tyrosine kinase activity
          protein binding
          ATP binding
          protein phosphatase type 2A regulator activity
          poly(A) RNA binding

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