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          System Message

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          LOADING ...
          See other JAK2 SIRNA Assays ›
          Gene Symbol:
          Jak2
          Gene Name:
          Janus kinase 2
          Gene Aliases:
          Fd17
          Chromosome Location:
          Chr.19: 29251776 - 29313080 on Build GRCm38
          UniGene ID:
          Mm.275839
          Species:
          Mouse
          Species Specific ID (Flybase ID):
          -
          siRNA ID 154959

          Purification
          Size
          Availability Inventoried
          Catalog # AM16708
          Price
          Your Price
          Online offer:
          Check your price ›
          • Genomic Map
          • siRNA Details
          • More Information

          Genomic Map

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          siRNA Details

          Gene Symbol: Jak2
          Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
          RefSeq NM_001048177.2 NP_001041642.1 2 457
          NM_008413.3 NP_032439.2 3 540
          GenBank mRNA AK087255.1 - 2 422
          BC054807.1 - 2 220 6838318
          BC059834.1 - 2 220 6838318
          BE981299.1 - 3 345
          L16956.1 - 2 209

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          More Information


          Gene Ontology Categories:

          Function(s) Process(es)

          activation of MAPKK activity
          immune system process
          protein phosphorylation
          activation of cysteine-type endopeptidase activity involved in apoptotic process
          response to oxidative stress
          signal transduction
          enzyme linked receptor protein signaling pathway
          transmembrane receptor protein tyrosine kinase signaling pathway
          G-protein coupled receptor signaling pathway
          positive regulation of cytosolic calcium ion concentration
          JAK-STAT cascade
          tyrosine phosphorylation of STAT protein
          STAT protein import into nucleus
          positive regulation of cell proliferation
          negative regulation of cell proliferation
          intrinsic apoptotic signaling pathway in response to oxidative stress
          hormone-mediated signaling pathway
          negative regulation of cardiac muscle cell apoptotic process
          positive regulation of cell-substrate adhesion
          positive regulation of phosphatidylinositol 3-kinase signaling
          phosphorylation
          cell migration
          chromatin modification
          peptidyl-tyrosine phosphorylation
          cytokine-mediated signaling pathway
          negative regulation of cell-cell adhesion
          myeloid cell differentiation
          cell differentiation
          regulation of cell adhesion
          erythrocyte differentiation
          positive regulation of cell migration
          axon regeneration
          mineralocorticoid receptor signaling pathway
          positive regulation of insulin secretion
          response to lipopolysaccharide
          positive regulation of phosphoprotein phosphatase activity
          positive regulation of interleukin-1 beta production
          positive regulation of tumor necrosis factor production
          positive regulation of protein import into nucleus, translocation
          response to hydroperoxide
          tumor necrosis factor-mediated signaling pathway
          host programmed cell death induced by symbiont
          response to tumor necrosis factor
          histone H3-Y41 phosphorylation
          intracellular signal transduction
          interleukin-12-mediated signaling pathway
          peptidyl-tyrosine autophosphorylation
          tyrosine phosphorylation of Stat3 protein
          tyrosine phosphorylation of Stat5 protein
          tyrosine phosphorylation of Stat1 protein
          positive regulation of tyrosine phosphorylation of Stat3 protein
          positive regulation of tyrosine phosphorylation of Stat5 protein
          activation of JAK2 kinase activity
          positive regulation of apoptotic process
          negative regulation of apoptotic process
          positive regulation of DNA binding
          negative regulation of DNA binding
          negative regulation of neuron apoptotic process
          innate immune response
          positive regulation of nitric oxide biosynthetic process
          positive regulation of cell differentiation
          negative regulation of heart contraction
          positive regulation of transcription from RNA polymerase II promoter
          response to antibiotic
          protein autophosphorylation
          platelet-derived growth factor receptor signaling pathway
          regulation of inflammatory response
          positive regulation of inflammatory response
          positive regulation of peptidyl-tyrosine phosphorylation
          positive regulation of cell activation
          positive regulation of sequence-specific DNA binding transcription factor activity
          positive regulation of nitric-oxide synthase biosynthetic process
          interferon-gamma-mediated signaling pathway
          growth hormone receptor signaling pathway
          JAK-STAT cascade involved in growth hormone signaling pathway
          positive regulation of growth hormone receptor signaling pathway
          mammary gland epithelium development
          response to interleukin-12
          cellular response to lipopolysaccharide
          cellular response to dexamethasone stimulus
          response to granulocyte macrophage colony-stimulating factor
          extrinsic apoptotic signaling pathway
          activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway
          positive regulation of apoptotic signaling pathway
          nucleotide binding
          protein kinase activity
          protein tyrosine kinase activity
          non-membrane spanning protein tyrosine kinase activity
          receptor binding
          growth hormone receptor binding
          interleukin-12 receptor binding
          protein binding
          ATP binding
          protein C-terminus binding
          kinase activity
          transferase activity
          transferase activity, transferring phosphorus-containing groups
          protein kinase binding
          heme binding
          type 1 angiotensin receptor binding
          acetylcholine receptor binding
          histone kinase activity (H3-Y41 specific)
          SH2 domain binding
          histone binding
          phosphatidylinositol 3-kinase binding
          insulin receptor substrate binding
          peptide hormone receptor binding

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