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          System Message

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          LOADING ...
          See other KDR SIRNA Assays ›
          Gene Symbol:
          KDR
          Gene Name:
          kinase insert domain receptor
          Gene Aliases:
          CD309, FLK1, VEGFR, VEGFR2
          Chromosome Location:
          Chr.4: 55078259 - 55125595 on Build GRCh38
          UniGene ID:
          Hs.479756
          Species:
          Human
          Species Specific ID (Flybase ID):
          -
          siRNA ID 222

          Purification
          Size
          Availability Inventoried
          Catalog # AM16708
          Price 4,126.00
          Your Price
          Online offer:
          4126.0
          Check your price ›
          • Genomic Map
          • siRNA Details
          • More Information

          Genomic Map

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          siRNA Details

          Gene Symbol: KDR
          Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
          RefSeq NM_002253.2 NP_002244.1 11, 12 1835
          GenBank mRNA AB209901.1 - 11, 12 1820
          AF035121.1 - 11, 12 1836
          AF063658.1 - 11, 12 1533
          BC131822.1 - 11, 12 1595 40129287
          EU826563.1 - 11, 12 1533
          FJ899739.1 - 11, 12 1533
          L04947.1 - 11, 12 1527
          X61656.1 - 11, 12 1527

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          More Information


          Other Species Targeted

          This siRNA also targets the following transcripts in Rat: NM_013062, BC087029, U93307, U93306.
          This siRNA also targets the following transcripts in Mouse: NM_010612, X70842, BC020530, EU884114, X59397, and others.

          Panther Classification:

          Molecular Function -

          transmembrane signal receptor

          Gene Ontology Categories:

          Function(s) Process(es)

          angiogenesis
          vasculogenesis
          positive regulation of protein phosphorylation
          positive regulation of endothelial cell proliferation
          cell migration involved in sprouting angiogenesis
          endothelium development
          transmembrane receptor protein tyrosine kinase signaling pathway
          positive regulation of cell proliferation
          regulation of cell shape
          positive regulation of endothelial cell migration
          positive regulation of phosphatidylinositol 3-kinase signaling
          viral process
          positive regulation of macroautophagy
          peptidyl-tyrosine phosphorylation
          signal transduction by protein phosphorylation
          extracellular matrix organization
          positive regulation of cell migration
          embryonic hemopoiesis
          calcium-mediated signaling using intracellular calcium source
          cellular response to vascular endothelial growth factor stimulus
          positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway
          peptidyl-tyrosine autophosphorylation
          negative regulation of apoptotic process
          positive regulation of MAPK cascade
          positive regulation of angiogenesis
          protein autophosphorylation
          vascular endothelial growth factor receptor signaling pathway
          positive regulation of positive chemotaxis
          positive regulation of nitric-oxide synthase biosynthetic process
          positive regulation of focal adhesion assembly
          positive regulation of mitochondrial depolarization
          positive regulation of ERK1 and ERK2 cascade
          positive regulation of mitochondrial fission
          negative regulation of endothelial cell apoptotic process
          positive regulation of vasculogenesis
          protein tyrosine kinase activity
          transmembrane receptor protein tyrosine kinase activity
          receptor signaling protein tyrosine kinase activity
          vascular endothelial growth factor-activated receptor activity
          integrin binding
          protein binding
          ATP binding
          growth factor binding
          Hsp90 protein binding

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