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          System Message

          OKCancel
          LOADING ...
          See other INSR SIRNA Assays ›
          Gene Symbol:
          INSR
          Gene Name:
          insulin receptor
          Gene Aliases:
          CD220, HHF5
          Chromosome Location:
          Chr.19: 7112255 - 7294405 on Build GRCh38
          UniGene ID:
          Hs.465744
          Species:
          Human
          Species Specific ID (Flybase ID):
          -
          siRNA ID 31

          Purification
          Size
          Availability Inventoried
          Catalog # AM51331
          Price 6,301.00
          Your Price
          Online offer:
          6301.0
          Check your price ›
          • Genomic Map
          • siRNA Details
          • More Information

          Genomic Map

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          siRNA Details

          Gene Symbol: INSR
          Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
          RefSeq NM_000208.3 NP_000199.2 21 4151
          NM_001079817.2 NP_001073285.1 20 4115
          XM_011527988.2 XP_011526290.2 21 4251
          XM_011527989.2 XP_011526291.2 20 4214
          GenBank mRNA AB208861.1 - 13 2093
          AK300332.1 - 1 82
          BC117172.1 - 20 3737 40125723
          M10051.1 - 21 3878
          X02160.1 - 20 3752

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          More Information


          Other Species Targeted

          This siRNA also targets the following transcripts in Rat: NM_017071, XM_006248753, XM_006248752, KF112847, KF112848, and others.

          Panther Classification:

          Molecular Function -

          transmembrane signal receptor

          Gene Ontology Categories:

          Function(s) Process(es)

          activation of MAPK activity
          negative regulation of protein phosphorylation
          positive regulation of protein phosphorylation
          heart morphogenesis
          carbohydrate metabolic process
          regulation of transcription, DNA-templated
          G-protein coupled receptor signaling pathway
          positive regulation of cell proliferation
          insulin receptor signaling pathway
          epidermis development
          male gonad development
          response to manganese ion
          regulation of hydrogen peroxide metabolic process
          positive regulation of glycoprotein biosynthetic process
          negative regulation of gene expression
          response to activity
          peptidyl-tyrosine phosphorylation
          transformation of host cell by virus
          signal transduction by protein phosphorylation
          male sex determination
          adrenal gland development
          positive regulation of cell migration
          exocrine pancreas development
          activation of protein kinase activity
          activation of protein kinase B activity
          response to estradiol
          negative regulation of transporter activity
          cellular response to insulin stimulus
          response to vitamin D
          response to testosterone
          response to tumor necrosis factor
          peptidyl-tyrosine autophosphorylation
          glucose homeostasis
          positive regulation of MAPK cascade
          positive regulation of nitric oxide biosynthetic process
          fat cell differentiation
          response to ethanol
          positive regulation of glycogen biosynthetic process
          positive regulation of DNA replication
          positive regulation of glycolytic process
          positive regulation of mitotic nuclear division
          positive regulation of transcription, DNA-templated
          regulation of embryonic development
          positive regulation of glucose import
          protein autophosphorylation
          positive regulation of developmental growth
          protein heterotetramerization
          response to glucocorticoid
          positive regulation of meiotic cell cycle
          positive regulation of protein kinase B signaling
          positive regulation of respiratory burst
          cellular response to growth factor stimulus
          regulation of female gonad development
          protein tyrosine kinase activity
          receptor signaling protein tyrosine kinase activity
          insulin-activated receptor activity
          insulin-like growth factor receptor binding
          protein binding
          ATP binding
          GTP binding
          protein phosphatase binding
          lipoic acid binding
          insulin-like growth factor I binding
          insulin-like growth factor II binding
          protein complex binding
          3-phosphoinositide-dependent protein kinase binding
          phosphatidylinositol 3-kinase binding
          insulin binding
          insulin receptor substrate binding
          PTB domain binding

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          Host server : magellan-search-blue-55ff9ddd88-49ts5:80/100.66.72.225:80.
          git-commit: d366ff9721d93504b2ac26a183b2b3e3d0e7d9ec
          git-url: https://github.com/thermofisher/magellan-search
          git-branch: release/2.42.0-2026.01.03-1.0