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          System Message

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          LOADING ...
          See other LYN SIRNA Assays ›
          Gene Symbol:
          Lyn
          Gene Name:
          LYN proto-oncogene, Src family tyrosine kinase
          Gene Aliases:
          p53Lyn, p56Lyn
          Chromosome Location:
          Chr.5: 16526058 - 16642648 on Build Rnor_6.0
          UniGene ID:
          Rn.4338
          Species:
          Rat
          Species Specific ID (Flybase ID):
          -
          siRNA ID 53226

          Purification
          Size
          Availability Inventoried
          Catalog # AM16708
          Price
          Your Price
          Online offer:
          Check your price ›
          • Genomic Map
          • siRNA Details
          • More Information

          Genomic Map

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          siRNA Details

          Gene Symbol: Lyn
          Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
          RefSeq NM_001111098.1 NP_001104568.1 4 434
          NM_030857.2 NP_110484.1 4 497
          XM_006237834.2 XP_006237896.1 4 813
          GenBank mRNA AF000300.1 - 4 342
          AF000301.1 - 4 434
          AF000302.1 - 4 432
          L14782.1 - 3 291
          L14823.1 - 3 228
          L14951.1 - 4 500

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          More Information


          Other Species Targeted

          This siRNA also targets the following transcripts in Mouse: NM_010747, NM_001111096, BC031547, M64608, M57697, and others.

          Gene Ontology Categories:

          Function(s) Process(es)

          B cell homeostasis
          regulation of cytokine production
          negative regulation of protein phosphorylation
          Fc receptor mediated stimulatory signaling pathway
          tolerance induction to self antigen
          histamine secretion by mast cell
          platelet degranulation
          negative regulation of myeloid leukocyte differentiation
          immune response-regulating cell surface receptor signaling pathway
          Fc receptor mediated inhibitory signaling pathway
          regulation of B cell apoptotic process
          protein phosphorylation
          chemotaxis
          cellular response to DNA damage stimulus
          response to sterol depletion
          transmembrane receptor protein tyrosine kinase signaling pathway
          positive regulation of cell proliferation
          negative regulation of cell proliferation
          response to toxic substance
          response to hormone
          response to carbohydrate
          positive regulation of neuron projection development
          oligodendrocyte development
          response to organic cyclic compound
          cell migration
          peptidyl-tyrosine phosphorylation
          hemopoiesis
          erythrocyte differentiation
          positive regulation of cell migration
          negative regulation of B cell proliferation
          neuron projection development
          lipopolysaccharide-mediated signaling pathway
          cellular response to extracellular stimulus
          response to insulin
          regulation of mast cell activation
          regulation of cell adhesion mediated by integrin
          negative regulation of toll-like receptor 2 signaling pathway
          negative regulation of toll-like receptor 4 signaling pathway
          cellular response to heat
          intracellular signal transduction
          peptidyl-tyrosine autophosphorylation
          positive regulation of phosphorylation
          response to drug
          positive regulation of tyrosine phosphorylation of STAT protein
          response to amino acid
          regulation of mast cell degranulation
          negative regulation of MAP kinase activity
          response to peptide hormone
          positive regulation of phosphatidylinositol 3-kinase activity
          innate immune response
          regulation of erythrocyte differentiation
          protein autophosphorylation
          response to axon injury
          cytokine secretion
          regulation of cytokine secretion
          regulation of inflammatory response
          positive regulation of peptidyl-tyrosine phosphorylation
          B cell receptor signaling pathway
          regulation of B cell receptor signaling pathway
          positive regulation of B cell receptor signaling pathway
          positive regulation of cellular component movement
          regulation of release of sequestered calcium ion into cytosol
          positive regulation of glial cell proliferation
          positive regulation of Fc receptor mediated stimulatory signaling pathway
          positive regulation of stress-activated protein kinase signaling cascade
          regulation of ERK1 and ERK2 cascade
          negative regulation of ERK1 and ERK2 cascade
          positive regulation of oligodendrocyte progenitor proliferation
          negative regulation of mast cell proliferation
          positive regulation of mast cell proliferation
          cellular response to retinoic acid
          cellular response to peptide hormone stimulus
          regulation of monocyte chemotaxis
          regulation of platelet aggregation
          dendritic cell differentiation
          negative regulation of intracellular signal transduction
          positive regulation of dendritic cell apoptotic process
          protein kinase activity
          protein tyrosine kinase activity
          non-membrane spanning protein tyrosine kinase activity
          receptor binding
          platelet-derived growth factor receptor binding
          integrin binding
          protein binding
          ATP binding
          kinase activity
          SH3 domain binding
          enzyme binding
          ubiquitin protein ligase binding
          protein complex binding
          gamma-tubulin binding
          glycosphingolipid binding
          ion channel binding
          phosphoprotein binding

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          Host server : magellan-search-blue-55ff9ddd88-mgl5f:80/100.66.79.229:80.
          git-commit: d366ff9721d93504b2ac26a183b2b3e3d0e7d9ec
          git-url: https://github.com/thermofisher/magellan-search
          git-branch: release/2.42.0-2026.01.03-1.0