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          System Message

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          LOADING ...
          See other PSEN1 SIRNA Assays ›
          Gene Symbol:
          Psen1
          Gene Name:
          presenilin 1
          Gene Aliases:
          Ad3h, PS-1, PS1, S182
          Chromosome Location:
          Chr.12: 83688146 - 83738446 on Build GRCm38
          UniGene ID:
          Mm.998
          Species:
          Mouse
          Species Specific ID (Flybase ID):
          -
          siRNA ID 63802

          Purification
          Size
          Availability Inventoried
          Catalog # AM16708
          Price 4,126.00
          Your Price
          Online offer:
          4126.0
          Check your price ›
          • Genomic Map
          • siRNA Details
          • More Information

          Genomic Map

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          siRNA Details

          Gene Symbol: Psen1
          Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
          RefSeq NM_008943.2 NP_032969.1 4 682
          GenBank mRNA AK134232.1 - 4 365
          AK134615.1 - 4 404
          AK165984.1 - 4 403
          BC014744.1 - 4 433 4511140
          BC030409.1 - 4 357 5133302
          BC071233.1 - 4 421 3673609
          L42177.1 - 4 378

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          More Information


          Panther Classification:

          Molecular Function -

          aspartic protease

          Gene Ontology Categories:

          Function(s) Process(es)

          autophagosome assembly
          negative regulation of transcription from RNA polymerase II promoter
          activation of MAPKK activity
          blood vessel development
          cell fate specification
          somitogenesis
          neuron migration
          positive regulation of receptor recycling
          negative regulation of protein phosphorylation
          positive regulation of protein phosphorylation
          heart looping
          hematopoietic progenitor cell differentiation
          T cell activation involved in immune response
          myeloid leukocyte differentiation
          negative regulation of protein kinase activity
          protein glycosylation
          proteolysis
          membrane protein ectodomain proteolysis
          calcium ion transport
          mitochondrial transport
          cellular calcium ion homeostasis
          autophagy
          apoptotic process
          cellular response to DNA damage stimulus
          response to oxidative stress
          cell adhesion
          negative regulation of epidermal growth factor-activated receptor activity
          regulation of epidermal growth factor-activated receptor activity
          Notch signaling pathway
          Notch receptor processing
          brain development
          heart development
          learning or memory
          memory
          embryo development
          post-embryonic development
          protein transport
          L-glutamate transport
          choline transport
          synaptic vesicle targeting
          single organismal cell-cell adhesion
          protein processing
          cerebral cortex cell migration
          Cajal-Retzius cell differentiation
          dorsal/ventral neural tube patterning
          cerebral cortex development
          neurogenesis
          neuron differentiation
          embryonic limb morphogenesis
          forebrain development
          positive regulation of proteasomal ubiquitin-dependent protein catabolic process
          endoplasmic reticulum calcium ion homeostasis
          beta-amyloid formation
          segmentation
          intracellular signal transduction
          locomotion
          regulation of phosphorylation
          anagen
          amyloid precursor protein catabolic process
          myeloid dendritic cell differentiation
          positive regulation of apoptotic process
          negative regulation of apoptotic process
          positive regulation of catalytic activity
          regulation of protein binding
          positive regulation of MAP kinase activity
          negative regulation of neuron apoptotic process
          skin morphogenesis
          cellular protein metabolic process
          positive regulation of protein kinase activity
          positive regulation of transcription, DNA-templated
          regulation of synaptic plasticity
          thymus development
          neuron development
          skeletal system morphogenesis
          brain morphogenesis
          beta-amyloid metabolic process
          epithelial cell proliferation
          negative regulation of axonogenesis
          positive regulation of coagulation
          T cell receptor signaling pathway
          neuron apoptotic process
          negative regulation of ubiquitin-protein transferase activity
          smooth endoplasmic reticulum calcium ion homeostasis
          protein maturation
          regulation of synaptic transmission, glutamatergic
          canonical Wnt signaling pathway
          regulation of resting membrane potential
          positive regulation of dendritic spine development
          calcium ion transmembrane transport
          negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
          negative regulation of apoptotic signaling pathway
          endopeptidase activity
          aspartic-type endopeptidase activity
          calcium channel activity
          protein binding
          beta-catenin binding
          peptidase activity
          hydrolase activity
          PDZ domain binding
          aspartic endopeptidase activity, intramembrane cleaving
          cadherin binding

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